S-tert-butyl O,O-diethyl phosphorothioate

Base Information

• Chemical Name: S-tert-butyl O,O-diethyl phosphorothioate
• CAS No.: 7795-74-6
• Molecular Formula: C8H19O3PS
• Molecular Weight: 226.277
• Mol file: 7795-74-6.mol

Synonyms:

Chemical Property of S-tert-butyl O,O-diethyl phosphorothioate

Chemical Property:

• Vapor Pressure: 0.022mmHg at 25°C
• Boiling Point: 258.6°Cat760mmHg
• Flash Point: 110.2°C
• Density: 1.069g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of S-tert-butyl O,O-diethyl phosphorothioate

There total 4 articles about S-tert-butyl O,O-diethyl phosphorothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

Thiophosphorsaeure-O,O-diethylester (2465-65-8) + 1,3-dioxoisoindolin-2-yl 3,3-dimethylbutanoate (84379-72-6) → diethyl S-tert-butyl thiophosphate (7795-74-6)

Guidance literature:

With potassium hydrogen difluoride; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; In acetonitrile; at 20 ℃; for 12h; Schlenk technique; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.1c02300

Reference yield:

tri-n-butyl phosphite (102-85-2) + bis(diethylphosphoryl)disulfide (4403-51-4) → tetraethyl thiopyrophosphate (645-78-3) + sulfotep (3689-24-5) + diethyl S-tert-butyl thiophosphate (7795-74-6) + C12H28O6P2S

Guidance literature:

With trineopentyl phosphite; In dichloromethane; Further byproducts given. Title compound not separated from byproducts; 1.) -70 deg C -> room temperature, 2.) room temperature, 30 min;

Reference yield:

Thiophosphorsaeure-O,O-diethylester (2465-65-8) + isobutene (115-11-7,15220-85-6) → diethyl S-tert-butyl thiophosphate (7795-74-6)

Guidance literature:

With hydroquinone;

DOI:10.1021/jo01344a051

upstream raw materials:

diethyl chlorophosphate

2-methylpropan-2-thiol

Thiophosphorsaeure-O,O-diethylester

isobutene