5-(dimethylamino)-3-{[methyl(propyl)amino]methyl}naphthalene-1-sulfonamide

Base Information

• Chemical Name: 5-(dimethylamino)-3-{[methyl(propyl)amino]methyl}naphthalene-1-sulfonamide
• CAS No.: 30003-07-7
• Molecular Formula: C17H25 N3 O2 S
• Molecular Weight: 335.47
• Mol file: 30003-07-7.mol

Synonyms:1-(5-Dimethylaminonaphthalene-1-sulfonamido)-3-N,N-dimethylaminopropane;1-(Dimethylamino)-3-[5-(dimethylamino)-1-naphthalenesulfonamido]propane;5-Dimethylaminonaphthalene-1-sulfonamido-N,N-dimethyl-n-propylamine;N'-Dansyl-N,N-dimethyl-1,3-diaminopropane

Chemical Property of 5-(dimethylamino)-3-{[methyl(propyl)amino]methyl}naphthalene-1-sulfonamide

Chemical Property:

• Vapor Pressure: 9.57E-10mmHg at 25°C
• Boiling Point: 489.9°Cat760mmHg
• Flash Point: 250.1°C
• Density: 1.197g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-(dimethylamino)-3-{[methyl(propyl)amino]methyl}naphthalene-1-sulfonamide

There total 1 articles about 5-(dimethylamino)-3-{[methyl(propyl)amino]methyl}naphthalene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

5-(dimethylamino)naphth-1-ylsulfonyl chloride (605-65-2) + 1-amino-3-(dimethylamino)propane (109-55-7) → 5-(dimethylamino)-N-(3-(dimethylamino)propyl)naphthalene-1-sulfonamide (30003-07-7)

Guidance literature:

With triethylamine; In dichloromethane; at 23 ℃; for 1h; Time; Temperature; Inert atmosphere; Reflux;

DOI:10.1039/c3tb21633k

Reference yield: 93.5%

4-O-(6-iodohexyl)benzophenone (54974-75-3) + 5-(dimethylamino)-N-(3-(dimethylamino)propyl)naphthalene-1-sulfonamide (30003-07-7) → 6-(4-benzoylphenoxy)-N-(3-(5-(dimethylamino)naphthalene-1-sulfonamido)propyl)-N,N-dimethylhexan-1-ammonium iodide (1572037-58-1)

Guidance literature:

In acetonitrile; at 100 ℃; for 24h; Temperature; Time;

DOI:10.1039/c3tb21633k

Reference yield: 87.8%

5-(dimethylamino)-N-(3-(dimethylamino)propyl)naphthalene-1-sulfonamide (30003-07-7) + 4-[(6-bromohexyl)oxy]benzophenone (74992-91-9) → 6-(4-benzoylphenoxy)-N-(3-(5-(dimethylamino)naphthalene-1-sulfonamido)propyl)-N,N-dimethylhexan-1-ammonium bromide (1572037-56-9)

Guidance literature:

In acetonitrile; at 100 ℃; for 24h; Temperature; Time;

DOI:10.1039/c3tb21633k

upstream raw materials:

5-(dimethylamino)naphth-1-ylsulfonyl chloride

1-amino-3-(dimethylamino)propane

Downstream raw materials:

N-dansyl-3-(trimethylamino)propylamine iodide

3-(4-benzoylphenoxy)-N-(3-(5-(dimethylamino)naphthalene-1-sulfonamido)propyl)-N,N-dimethylpropan-1-ammonium iodide

4-(4-benzoylphenoxy)-N-(3-(5-(dimethylamino)naphthalene-1-sulfonamido)propyl)-N,N-dimethylbutan-1-ammonium bromide

4-(4-benzoylphenoxy)-N-(3-(5-(dimethylamino)naphthalene-1-sulfonamido)propyl)-N,N-dimethylbutan-1-ammonium iodide