DPP RED

Base Information

• Chemical Name: DPP RED
• CAS No.: 88949-37-5
• Molecular Formula: C18H11 Cl N2 O2
• Molecular Weight: 322.751
• Hs Code.: 2933990090
• Mol file: 88949-37-5.mol

Synonyms:3-(4-Chlorophenyl)-6-phenyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

Chemical Property of DPP RED

Chemical Property:

• PSA: 61.69000
• LogP: 3.32670

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DPP RED

There total 5 articles about DPP RED which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

4-Cyanochlorobenzene (623-03-0) + 2,3-dihydro-2-oxo 5-phenyl-1H-pyrrole-4-carboxylic acid ethyl ester (105194-22-7) → 3-(4-chlorophenyl)-6-phenylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione (88949-37-5)

Guidance literature:

With sodium tert-pentoxide; for 2h; Inert atmosphere; Reflux;

DOI:10.1021/acs.cgd.5b01656

Reference yield:

4-Cyanochlorobenzene (623-03-0) + diisopropyl succinate (924-88-9) + benzonitrile (100-47-0) → 3-(4-chlorophenyl)-6-phenylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione (88949-37-5) + 3,6-bis(4-chlorophenyl)-2,5-dihydro-1,4-diketopyrrolo[3,4-c]pyrrole (84632-65-5,122390-98-1) + 3,6-diphenyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-(2H,5H)-dione (54660-00-3,120500-90-5)

Guidance literature:

With sodium tert-pentoxide; at 20 - 100 ℃; for 2h; Neat (no solvent);

Reference yield:

ethyl 3-oxo-3-phenylpropionate (94-02-0) → 3-(4-chlorophenyl)-6-phenylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione (88949-37-5)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate; sodium iodide / acetone; 1,2-dimethoxyethane / 24 h / Reflux

2: ammonium acetate; acetic acid / 3 h / Reflux

3: sodium tert-pentoxide / 2 h / Inert atmosphere; Reflux

With ammonium acetate; sodium tert-pentoxide; potassium carbonate; acetic acid; sodium iodide; In 1,2-dimethoxyethane; acetone;

DOI:10.1021/acs.cgd.5b01656

upstream raw materials:

4-Cyanochlorobenzene

diisopropyl succinate

benzonitrile

2,3-dihydro-2-oxo 5-phenyl-1H-pyrrole-4-carboxylic acid ethyl ester

Downstream raw materials:

C₁₈H₁₀ClN₂O₅S^(1-)*Na⁽¹⁺⁾