9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine

Base Information

Chemical Name:9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine
CAS No.:103884-98-6
Molecular Formula:C10H12FN5O4
Molecular Weight:285.235
Hs Code.:
Mol file:103884-98-6.mol

Synonyms:2-amino-9-(2-deoxy-2-fluoro-D-arabinofuranosyl)-3,9-dihydro-6H-purin-6-one;6H-purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-D-arabinofuranosyl)-1,9-dihydro-;9-(2-deoxy-2-fluoroarabinofuranosyl)guanine;9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)guanine;

Suppliers and Price of 9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
9-(2''-Deoxy-2''-fluoro-b-D-arabinofuranosyl)guanine
25mg
$ 175.00

TRC
9-(2''-Deoxy-2''-fluoro-b-D-arabinofuranosyl)guanine
5mg
$ 60.00

DC Chemicals
9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine
002
$ 750.00

Crysdot
9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine 95+%
100mg
$ 990.00

Chemenu
2-amino-9-((3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one 95%
100mg
$ 926.00

Biosynth Carbosynth
9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine
10 mg
$ 45.00

Biosynth Carbosynth
9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine
50 mg
$ 150.00

Biosynth Carbosynth
9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine
250 mg
$ 500.00

Biosynth Carbosynth
9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine
100 mg
$ 250.00

Biosynth Carbosynth
9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine
25 mg
$ 90.00

Total 43 raw suppliers

Chemical Property of 9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine

Chemical Property:

Vapor Pressure:3.94E-22mmHg at 25°C
Melting Point:275-279 °C
Refractive Index:1.876
Boiling Point:726.1 °C at 760 mmHg
PKA:12.68±0.70(Predicted)
Flash Point:392.9 °C
PSA：139.28000
Density:2.17 g/cm³
LogP:-1.12830

Purity/Quality:

99% ^*data from raw suppliers

9-(2''-Deoxy-2''-fluoro-b-D-arabinofuranosyl)guanine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Use Description 9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine, also known as F-ara-G, is a chemical compound with significant applications in various fields. In the pharmaceutical industry, it is used as an antiviral agent, particularly against viruses such as HIV and hepatitis B and C. Its role in medicine is vital, as it helps inhibit viral replication and can be incorporated into nucleic acids during viral DNA synthesis. Additionally, in the field of molecular biology and genetics, F-ara-G serves as a valuable tool for studying DNA replication, repair, and transcription processes. Its incorporation into DNA strands can help researchers investigate the effects of nucleoside analogs on these biological processes. Furthermore, in cancer research and therapy, it may be employed in experimental treatments due to its potential to inhibit DNA synthesis in rapidly dividing cancer cells. Its adaptability as an antiviral agent and a molecular biology tool underscores its significance in advancing medicine, genetics, and cancer research.

Technology Process of 9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine

There total 26 articles about 9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 103884-97-5
9-(2’-deoxy-2’-fluoro-β-D-arabinofuranos-1’-yl)-2-amino-6-aminopurine

: 103884-98-6
9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-guanine

Guidance literature:: With hydrogenchloride; Tris buffer; adenosine deaminase; In water; at 20 ℃; for 1.5h; pH=7.0; Acidic aqueous solution; Enzymatic reaction;

Reference yield: 91.0%

: 3',5'-Di-O-trityl-F-ara-G

: 103884-98-6
9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-guanine

Guidance literature:: With trifluoroacetic acid; In chloroform; for 3h; Ambient temperature;
DOI:10.1021/jo00052a055

Reference yield: 87.0%

: 144924-88-9
9-(2'-deoxy-2'-fluoro-β-D-arabinofuranos-1'-yl)-2-amino-6-chloropurine

: 103884-98-6
9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-guanine

Guidance literature:: With adenosine deaminase from calf intestinal mucosa; In aq. phosphate buffer; at 25 ℃; for 19h; pH=7.4; Enzymatic reaction;
DOI:10.1016/j.tetlet.2015.11.091