2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside

Base Information

Chemical Name:2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside
CAS No.:118373-61-8
Molecular Formula:C24H19ClFN5O5
Molecular Weight:511.897
Hs Code.:
Mol file:118373-61-8.mol

Synonyms:2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside;2-AMino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-β-D-arabinofuranosyl)-9H-purine;6-Chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-2-amine

Suppliers and Price of 2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2R,3R,4S,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-2-((benzoyloxy)methyl)-4-fluorotetrahydrofuran-3-ylbenzoate 97%
1g
$ 1140.00

Chemenu
(2R,3R,4S,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-((benzoyloxy)methyl)-4-fluorotetrahydrofuran-3-ylbenzoate 97%
1g
$ 1066.00

Biosynth Carbosynth
2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine
5 g
$ 1102.50

Biosynth Carbosynth
2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine
2 g
$ 546.00

Biosynth Carbosynth
2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine
1 g
$ 367.50

Biosynth Carbosynth
2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine
25 g
$ 3281.50

Biosynth Carbosynth
2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine
10 g
$ 1575.00

Alichem
(2R,3R,4S,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-2-((benzoyloxy)methyl)-4-fluorotetrahydrofuran-3-ylbenzoate
1g
$ 1151.40

AK Scientific
CID14016765
5g
$ 1538.00

Total 7 raw suppliers

Chemical Property of 2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside

Chemical Property:

Boiling Point:735.1±70.0 °C(Predicted)
PKA:1.69±0.10(Predicted)
PSA：131.45000
Density:1.58±0.1 g/cm3(Predicted)
LogP:3.96120

Purity/Quality:

97% ^*data from raw suppliers

(2R,3R,4S,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-2-((benzoyloxy)methyl)-4-fluorotetrahydrofuran-3-ylbenzoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside

There total 13 articles about 2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 97614-44-3
2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide

: 10310-21-1
2-Amino-6-chloropurin

: 118373-61-8
2-amino-6-chloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)-9H-purine

Guidance literature:: With potassium tert-butylate; In tert-Amyl alcohol; 1,2-dichloro-ethane; acetonitrile; at 20 ℃; for 20h; Inert atmosphere;
DOI:10.1021/op800182x

Reference yield: 36.0%

: 97614-44-3
2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide

: 10310-21-1
2-amino-6-chloropurine

: 118373-61-8
2-amino-6-chloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)-9H-purine

Guidance literature:: 2-amino-6-chloropurine; With potassium tert-butylate; In 1,2-dimethoxyethane; at 20 ℃; for 1h;

2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide; In 1,2-dichloro-ethane; at 20 ℃; for 20h;

Reference yield: 17.0%

: (3S,4R,5R)-5-((benzoyloxy)methyl)-3-fluorotetrahydrofuran-2,4-diyl dibenzoate

: 10310-21-1
2-Amino-6-chloropurin

: 118373-61-8
2-amino-6-chloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)-9H-purine

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 0 - 65 ℃; for 21h;
DOI:10.1002/cmdc.201200562