1,4-Piperidinedicarboxylic acid, 4-[[[2,4-dichloro-3-[[(2,4-dimethyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl] amino]-, 1-(1,1-dimethylethyl) ester

Base Information

Chemical Name:1,4-Piperidinedicarboxylic acid, 4-[[[2,4-dichloro-3-[[(2,4-dimethyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl] amino]-, 1-(1,1-dimethylethyl) ester
CAS No.:928851-48-3
Molecular Formula:C29H33Cl2N3O7S
Molecular Weight:638.569
Hs Code.:

1,4-Piperidinedicarboxylic acid,
4-[[[2,4-dichloro-3-[[(2,4-dimethyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl]
amino]-, 1-(1,1-dimethylethyl) ester

Synonyms:

Suppliers and Price of 1,4-Piperidinedicarboxylic acid, 4-[[[2,4-dichloro-3-[[(2,4-dimethyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl] amino]-, 1-(1,1-dimethylethyl) ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,4-Piperidinedicarboxylic acid, 4-[[[2,4-dichloro-3-[[(2,4-dimethyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl] amino]-, 1-(1,1-dimethylethyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,4-Piperidinedicarboxylic acid, 4-[[[2,4-dichloro-3-[[(2,4-dimethyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl] amino]-, 1-(1,1-dimethylethyl) ester

There total 3 articles about 1,4-Piperidinedicarboxylic acid, 4-[[[2,4-dichloro-3-[[(2,4-dimethyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl] amino]-, 1-(1,1-dimethylethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1026484-91-2
4-(3-bromomethyl)-2,4-dichloro-phenylsulfonamido-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid

: 115310-98-0
8-hydroxy-2,4-dimethylquinoline

: 928851-48-3
4-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester

Guidance literature:: 8-hydroxy-2,4-dimethylquinoline; With lithium hydroxide; In acetonitrile; at 20 ℃; for 1.5h;

4-(3-bromomethyl)-2,4-dichloro-phenylsulfonamido-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid; In N,N-dimethyl-formamide; acetonitrile; at 20 ℃;
DOI:10.1021/jm061143k

Reference yield:

: 188440-21-3
3-bromomethyl-2,4-dichlorobenzenesulphonyl chloride

: 928851-48-3
4-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: trimethylsilyl chloride; N,O-bis-trimethylsilylacetamide / tetrahydrofuran / 2 h / Heating

1.2: tetrahydrofuran

1.3: NaBr / acetone; dimethylformamide / 20 °C

2.1: LiOH / acetonitrile / 1.5 h / 20 °C

2.2: acetonitrile; dimethylformamide / 20 °C

With lithium hydroxide; chloro-trimethyl-silane; N,O-bis-(trimethylsilyl)-acetamide; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm061143k

Reference yield:

: 69145-58-0
2,4-Dichloro-3-methylbenzenesulfonyl chloride

: 928851-48-3
4-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-bromosuccinimide; AIBN / CCl₄

2.1: trimethylsilyl chloride; N,O-bis-trimethylsilylacetamide / tetrahydrofuran / 2 h / Heating

2.2: tetrahydrofuran

2.3: NaBr / acetone; dimethylformamide / 20 °C

3.1: LiOH / acetonitrile / 1.5 h / 20 °C

3.2: acetonitrile; dimethylformamide / 20 °C

With lithium hydroxide; N-Bromosuccinimide; chloro-trimethyl-silane; N,O-bis-(trimethylsilyl)-acetamide; 2,2'-azobis(isobutyronitrile); In tetrahydrofuran; tetrachloromethane; acetonitrile;
DOI:10.1021/jm061143k