1-(2-bromoethyl)-3,5-dimethylbenzene

Base Information

• Chemical Name: 1-(2-bromoethyl)-3,5-dimethylbenzene
• CAS No.: 93427-11-3
• Molecular Formula: C₁₀H₁₃Br
• Molecular Weight: 213.117
• Mol file: 93427-11-3.mol

Synonyms:1-(2-BROMOETHYL)-3,5-DIMETHYLBENZENE;

Chemical Property of 1-(2-bromoethyl)-3,5-dimethylbenzene

Chemical Property:

• Boiling Point: 75-78 °C (0.5mmHg)
• PSA: 0.00000
• Density: 1.268±0.06 g/cm3 (20 °C, 760 mmHg)
• LogP: 3.24080

Purity/Quality:

99% ^*data from raw suppliers

1-(2-BROMOETHYL)-3,5-DIMETHYLBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-bromoethyl)-3,5-dimethylbenzene

There total 1 articles about 1-(2-bromoethyl)-3,5-dimethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

β-(3,5-Dimethylphenyl)ethyl alcohol (62343-67-3) → β-(3,5-Dimethylphenyl)ethyl bromide (93427-11-3)

Guidance literature:

With phosphorus tribromide; for 0.166667h; Heating;

DOI:10.1021/jo00200a022

Reference yield:

β-(3,5-Dimethylphenyl)ethyl bromide (93427-11-3) → β-(3,5-Dimethylphenyl)ethanesulfonamide (93427-12-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) anhydrous sodium sulfite 2) dimethylformamide, thionyl chloride / 1) water, reflux, 24 h 2) benzene, reflux, 4h

2: 85 percent / ammonia gas / diethyl ether / 2 h

With thionyl chloride; ammonia; N,N-dimethyl-formamide; sodium sulfite; In diethyl ether;

DOI:10.1021/jo00200a022

Reference yield:

β-(3,5-Dimethylphenyl)ethyl bromide (93427-11-3) → β-(3,5-Dimethylphenyl)ethanesulfonyl azide (70555-51-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) anhydrous sodium sulfite 2) dimethylformamide, thionyl chloride / 1) water, reflux, 24 h 2) benzene, reflux, 4h

2: 70 percent / Sodium azide / acetone; H₂O / 12 h / Ambient temperature

With thionyl chloride; sodium azide; N,N-dimethyl-formamide; sodium sulfite; In water; acetone;

DOI:10.1021/jo00200a022

upstream raw materials:

β-(3,5-Dimethylphenyl)ethyl alcohol

Downstream raw materials:

β-(3,5-Dimethylphenyl)ethanesulfonyl chloride

β-(3,5-Dimethylphenyl)ethanesulfonyl azide

3,5-dimethylstyrene

5,7-Dimethylindoline

Refernces