β-(3,5-Dimethylphenyl)ethanesulfonyl chloride

Base Information

• Chemical Name: β-(3,5-Dimethylphenyl)ethanesulfonyl chloride
• CAS No.: 88106-98-3
• Molecular Formula: C₁₀H₁₃ClO₂S
• Molecular Weight: 232.731
• Mol file: 88106-98-3.mol

Synonyms:β-(3,5-Dimethylphenyl)ethanesulfonyl chloride

Chemical Property of β-(3,5-Dimethylphenyl)ethanesulfonyl chloride

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of β-(3,5-Dimethylphenyl)ethanesulfonyl chloride

There total 2 articles about β-(3,5-Dimethylphenyl)ethanesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β-(3,5-Dimethylphenyl)ethyl bromide (93427-11-3) → β-(3,5-Dimethylphenyl)ethanesulfonyl chloride (88106-98-3)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; sodium sulfite; Yield given. Multistep reaction; 1) water, reflux, 24 h 2) benzene, reflux, 4h;

DOI:10.1021/jo00200a022

Reference yield:

β-(3,5-Dimethylphenyl)ethyl alcohol (62343-67-3) → β-(3,5-Dimethylphenyl)ethanesulfonyl chloride (88106-98-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 48 percent / Phosphorous tribromide / 0.17 h / Heating

2: 1) anhydrous sodium sulfite 2) dimethylformamide, thionyl chloride / 1) water, reflux, 24 h 2) benzene, reflux, 4h

With thionyl chloride; phosphorus tribromide; N,N-dimethyl-formamide; sodium sulfite;

DOI:10.1021/jo00200a022

Reference yield: 85.0%

β-(3,5-Dimethylphenyl)ethanesulfonyl chloride (88106-98-3) → β-(3,5-Dimethylphenyl)ethanesulfonamide (93427-12-4)

Guidance literature:

With ammonia; In diethyl ether; for 2h;

DOI:10.1021/jo00200a022

upstream raw materials:

β-(3,5-Dimethylphenyl)ethyl bromide

β-(3,5-Dimethylphenyl)ethyl alcohol

Downstream raw materials:

β-(3,5-Dimethylphenyl)ethanesulfonyl azide

β-(3,5-Dimethylphenyl)ethanesulfonamide

3,5-dimethylstyrene

5,7-Dimethylindoline