2-Cyclohexene-1-carboxylic acid, 1-(3-chloropropyl)-2-(trimethylstannyl)-, methyl ester

Base Information

Chemical Name:2-Cyclohexene-1-carboxylic acid, 1-(3-chloropropyl)-2-(trimethylstannyl)-, methyl ester
CAS No.:93512-05-1
Molecular Formula:C14H25ClO2Sn
Molecular Weight:379.514
Hs Code.:

Synonyms:

Suppliers and Price of 2-Cyclohexene-1-carboxylic acid, 1-(3-chloropropyl)-2-(trimethylstannyl)-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Cyclohexene-1-carboxylic acid, 1-(3-chloropropyl)-2-(trimethylstannyl)-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Cyclohexene-1-carboxylic acid, 1-(3-chloropropyl)-2-(trimethylstannyl)-, methyl ester

There total 1 articles about 2-Cyclohexene-1-carboxylic acid, 1-(3-chloropropyl)-2-(trimethylstannyl)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 93493-97-1
methyl 2-(trimethylstannyl)-1-cyclohexenecarboxylate

: 6940-76-7
1-iodo-3-chloro-propane

: 4111-54-0
lithium diisopropyl amide

: 93512-05-1
methyl 1-(3-chloropropyl)-2-(trimethylstannyl)-2-cyclohexenecarboxylate

Guidance literature:: With ammonium chloride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; Ar; addn. of a solution of the ester to a cold (-48 ° C) stirred solution of LDA in HMPA/THF; stirring at -48 ° C for 40 min; addn. of 1-chloro-3-iodopropane; stirring at this temperature for 40 min;; addn. of saturated aqueous NH4Cl; dilution at room temperature with Et2O; washing of the mixture with CuSO4, water, brine; drying (MgSO4), concentration; flash chromy., followed by distillation (125-135 ° C/0.1 Torr);

Reference yield: 90.0%

: 93512-05-1
methyl 1-(3-chloropropyl)-2-(trimethylstannyl)-2-cyclohexenecarboxylate

: 1191-15-7
diisobutylaluminium hydride

: 152564-14-2
3-(3-chloropropyl)-3-(hydroxymethyl)-2-(trimethylstannyl)-2-cyclohexene

Guidance literature:: With ammonium chloride; In diethyl ether; hexane; Ar; addn. of a solution of i-Bu2AlH in hexanes to a solution of the starting compound in ether at -20 ° C; stirring at -20 ° C for 1 h;; addn. of aqueous NH4Cl, stirring at rrom temperature until the organic phase was clear; filtration (florisil, ether); concentration; distillation (125-130 ° C/0.1 Torr);;