(1R,2R)-2-methylcyclohexane-1-carboxylic acid

Base Information

Chemical Name:(1R,2R)-2-methylcyclohexane-1-carboxylic acid
CAS No.:15177-62-5
Molecular Formula:C8H14 O2
Molecular Weight:142.198
Hs Code.:
European Community (EC) Number:239-227-7
DSSTox Substance ID:DTXSID701253881
Nikkaji Number:J215.927I
Mol file:15177-62-5.mol

Synonyms:15177-62-5;(1R,2R)-2-methylcyclohexane-1-carboxylic acid;Cyclohexanecarboxylic acid, 2-methyl-, trans-;SCHEMBL791505;DTXSID701253881;AKOS006379768;(A+/-)-trans-2-methyl-cyclohexanecarboxylic acid

Suppliers and Price of (1R,2R)-2-methylcyclohexane-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (1R,2R)-2-methylcyclohexane-1-carboxylic acid

Chemical Property:

Melting Point:170-172 °C
Boiling Point:242.2°Cat760mmHg
PKA:5.43±0.28(Predicted)
Flash Point:110.7°C
PSA：37.30000
Density:1.025g/cm³
LogP:1.89730
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:142.099379685
Heavy Atom Count:10
Complexity:131

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCCCC1C(=O)O
Isomeric SMILES:C[C@@H]1CCCC[C@H]1C(=O)O

Technology Process of (1R,2R)-2-methylcyclohexane-1-carboxylic acid

There total 45 articles about (1R,2R)-2-methylcyclohexane-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 591-49-1
1-methylcyclohex-1-ene

: 124-38-9,18923-20-1
carbon dioxide

: 15177-62-5
trans-2-methylcyclohexanecarboxylic acid

Guidance literature:: 1-methylcyclohex-1-ene; With 9-borabicyclo[3.3.1]nonane dimer; In 2-methyltetrahydrofuran; at 70 ℃; for 24h; Sealed tube;

carbon dioxide; With copper(l) iodide; cesium fluoride; sodium t-butanolate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; In 2-methyltetrahydrofuran; at 120 ℃; for 24h; regioselective reaction; Sealed tube;
DOI:10.1002/cssc.201903224

Reference yield:

: 201230-82-2
carbon monoxide

: 82166-21-0
methyl cyclohexane

: 5292-21-7
Cyclohexylacetic acid

: 13293-59-9,73873-48-0,73873-49-1,77954-16-6,77954-17-7
(+/-)-trans-3-methyl-cyclohexanecarboxylic acid

: 13293-59-9,73873-48-0,73873-49-1,77954-16-6,77954-17-7
(+/-)-cis-3-methyl-cyclohexanecarboxylic acid

: 15177-62-5
trans-2-methylcyclohexanecarboxylic acid

Guidance literature:: With dipotassium peroxodisulfate; trifluoroacetic acid; palladium diacetate; at 80 ℃; Further byproducts given;
DOI:10.1246/cl.1991.1433

Reference yield:

: 201230-82-2
carbon monoxide

: 82166-21-0
methyl cyclohexane

: 934-67-8,4331-54-8,13064-83-0
trans-4-methylcyclohexanecarboxylic acid

: 13293-59-9,73873-48-0,73873-49-1,77954-16-6,77954-17-7
(+/-)-trans-3-methyl-cyclohexanecarboxylic acid

: 13293-59-9,73873-48-0,73873-49-1,77954-16-6,77954-17-7
(+/-)-cis-3-methyl-cyclohexanecarboxylic acid

: 15177-62-5
trans-2-methylcyclohexanecarboxylic acid

Guidance literature:: With dipotassium peroxodisulfate; trifluoroacetic acid; palladium diacetate; at 80 ℃; Further byproducts given;
DOI:10.1246/cl.1991.1433