Pyruvoyl bromide 4-nitrophenylhydrazone

Base Information

• Chemical Name: Pyruvoyl bromide 4-nitrophenylhydrazone
• CAS No.: 55480-47-2
• Molecular Formula: C9H8 Br N3 O3
• Molecular Weight: 286.08212
• Mol file: 55480-47-2.mol

Synonyms:Pyruvoyl bromide 4-nitrophenylhydrazone;BRN 0659078;Pyruvoyl bromide, p-nitrophenylhydrazone;3-15-00-00382 (Beilstein Handbook Reference);C9H8BrN3O3;55480-47-2;C9-H8-Br-N3-O3;LS-139805

Chemical Property of Pyruvoyl bromide 4-nitrophenylhydrazone

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 395.012°C at 760 mmHg
• Flash Point: 192.696°C
• PSA: 87.28000
• Density: 1.656g/cm³
• LogP: 2.90030
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 284.97490
• Heavy Atom Count: 16
• Complexity: 306

Purity/Quality:

PYRUVOYL BROMIDE-PARA-NITROPHENYLHYDRAZONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)C(=NNC1=CC=C(C=C1)[N+](=O)[O-])Br
• Isomeric SMILES: CC(=O)/C(=N/NC1=CC=C(C=C1)[N+](=O)[O-])/Br

Technology Process of Pyruvoyl bromide 4-nitrophenylhydrazone

There total 3 articles about Pyruvoyl bromide 4-nitrophenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

pentane-2,3,4-trione-3-(4-nitro-phenylhydrazone) (50711-98-3) → N'-(4-nitro-phenyl)-pyruvohydrazonoyl bromide (55480-47-2)

Guidance literature:

With bromine; sodium acetate; acetic anhydride; In acetic acid; at 0 - 5 ℃; for 3h;

DOI:10.1021/je00026a022

Reference yield:

pentane-2,3,4-trione-3-(4-nitro-phenylhydrazone) (50711-98-3) → C9H8BrN3O3 (55480-47-2)

Guidance literature:

With bromine; sodium acetate; In acetic anhydride; acetic acid; at 0 - 5 ℃;

DOI:10.1016/S0040-4020(01)97638-0

Reference yield:

bromine (7726-95-6) + sodium acetate (127-09-3) + acetic acid (64-19-7,77671-22-8) + 1-(2-(4-nitrophenyl)hydrazono)propan-2-one (18804-75-6) → N'-(4-nitro-phenyl)-pyruvohydrazonoyl bromide (55480-47-2)

Guidance literature:

upstream raw materials:

pentane-2,3,4-trione-3-(4-nitro-phenylhydrazone)

bromine

sodium acetate

acetic acid

Downstream raw materials:

N-[3-Methyl-benzo[1,4]oxazin-(2E)-ylidene]-N'-(4-nitro-phenyl)-hydrazine

1-[3-Acetyl-5-methyl-1-(4-nitro-phenyl)-1H-pyrazol-4-yl]-ethanone

1-(4-Nitro-phenylazo)-1-(triphenyl-λ⁵-phosphanylidene)-propan-2-one

N-[3-Methyl-benzo[1,4]thiazin-(2E)-ylidene]-N'-(4-nitro-phenyl)-hydrazine

Refernces

• 1、 Tewari, Ram S.,Parihar, Padma. "Halogenation of Substituted Hydrazones. A Facile Route for the Synthesis of Some New Hydrazidoyl Halides". . p. 418 - 420. Retrieved 2007/10/02.