Technology Process of Carbamic acid, [2-[3,4-bis(acetyloxy)phenyl]-2-hydroxyethyl]-,
1,1-dimethylethyl ester
There total 7 articles about Carbamic acid, [2-[3,4-bis(acetyloxy)phenyl]-2-hydroxyethyl]-,
1,1-dimethylethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium cyanoborohydride; acetic acid;
In
tetrahydrofuran;
at 25 ℃;
for 4h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: TEA / dioxane
2: 2 N etheric HCl / dioxane / 0.25 h / 20 °C
3: 1.) KI; 2.) NaN3 / 1.) acetone, 15 min; acetone, 6 h, room temp.
4: 83 percent / H2 / Pd/C (5percent Pd) / dioxane / 18 h / 2206.5 Torr
5: 97 percent / acetic acid, sodium-cyano trihydroborate / tetrahydrofuran / 4 h / 25 °C
With
hydrogenchloride; sodium azide; TEA; hydrogen; sodium cyanoborohydride; acetic acid; potassium iodide;
5%-palladium/activated carbon;
In
tetrahydrofuran; 1,4-dioxane;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 84 percent / 2 h / Heating
2: 82 percent / SOCl2, pyridine / 1.5 h / Heating
3: TEA / dioxane
4: 2 N etheric HCl / dioxane / 0.25 h / 20 °C
5: 1.) KI; 2.) NaN3 / 1.) acetone, 15 min; acetone, 6 h, room temp.
6: 83 percent / H2 / Pd/C (5percent Pd) / dioxane / 18 h / 2206.5 Torr
7: 97 percent / acetic acid, sodium-cyano trihydroborate / tetrahydrofuran / 4 h / 25 °C
With
pyridine; hydrogenchloride; thionyl chloride; sodium azide; TEA; hydrogen; sodium cyanoborohydride; acetic acid; potassium iodide;
5%-palladium/activated carbon;
In
tetrahydrofuran; 1,4-dioxane;
