1H,4H-OCTAFLUOROBUTANE

Base Information

• Chemical Name: 1H,4H-OCTAFLUOROBUTANE
• CAS No.: 377-36-6
• Molecular Formula: C4H2F8
• Molecular Weight: 202.047
• Hs Code.: 2903399090
• Mol file: 377-36-6.mol

Synonyms:1,1,2,2,3,3,4,4-Octafluorobutane;1,4-Dihydrooctafluorobutane;1,4-Dihydroperfluorobutane;1H,4H-Perfluorobutane;HFC 338pcc;a,w-Dihydroperfluorobutane;

Chemical Property of 1H,4H-OCTAFLUOROBUTANE

Chemical Property:

• Vapor Pressure: 426mmHg at 25°C
• Melting Point: -79 ºC
• Refractive Index: 1.247
• Boiling Point: 41 °C at 760 mmHg
• PSA: 0.00000
• Density: 1.453 g/cm³
• LogP: 2.78720

Purity/Quality:

97% ^*data from raw suppliers

1H,4H-Octafluorobutane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: 23

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H,4H-OCTAFLUOROBUTANE

There total 8 articles about 1H,4H-OCTAFLUOROBUTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

6H-undecafluoro-hexan-2-one (42287-75-2) → 1,1,2,2,3,3,4,4-octafluorobutane (377-36-6) + trifluoroacetic acid (76-05-1)

Guidance literature:

With sodium hydroxide; sulfuric acid; Product distribution; 1.) H₂O, reflux, 30 min, 2.) reflux;

DOI:10.1007/BF01141717

Reference yield:

1,4-dibromo-1,1,2,2,3,3,4,4-octafluoro-butane (335-48-8) → 1,1,2,2,3,3,4,4-octafluorobutane (377-36-6) + hexafluoro-1,3-butadiene (685-63-2) + 4-H-heptafluoro-1-butene (680-54-6) + hexafluorocyclobut-1-ene (697-11-0)

Guidance literature:

With ethylmagnesium bromide; magnesium; In toluene; for 4h; Product distribution / selectivity; Heating / reflux;

Reference yield:

1,1,1,6-tetrahydrooctafluoro-2-hexanone (93449-49-1) → acetamide (60-35-5) + 1,1,2,2,3,3,4,4-octafluorobutane (377-36-6) + 1,1,1,6-tetrahydro-2-hydroxy-2-aminooctafluorohexane

Guidance literature:

In diethyl ether; ammonia; at 0 ℃;

upstream raw materials:

6H-undecafluoro-hexan-2-one

1,1,1,6-tetrahydrooctafluoro-2-hexanone

methanol

1,4-dibromo-1,1,2,2,3,3,4,4-octafluoro-butane