1,8-DIMETHOXYOCTANE

Base Information

• Chemical Name: 1,8-DIMETHOXYOCTANE
• CAS No.: 51306-09-3
• Molecular Formula: C10H22 O2
• Molecular Weight: 174.283
• NSC Number: 62126
• DSSTox Substance ID: DTXSID80289593
• Nikkaji Number: J443.628H
• Wikidata: Q82026956
• Mol file: 51306-09-3.mol

Synonyms:1,8-Dimethoxyoctane;NSC 62126

Chemical Property of 1,8-DIMETHOXYOCTANE

Chemical Property:

• Vapor Pressure: 0.299mmHg at 25°C
• Boiling Point: 209°Cat760mmHg
• Flash Point: 53.3°C
• PSA: 18.46000
• Density: 0.844g/cm³
• LogP: 2.61980
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 9
• Exact Mass: 174.161979940
• Heavy Atom Count: 12
• Complexity: 64.2

Purity/Quality:

1,8-dimethoxyoctane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCCCCCCCCOC

Technology Process of 1,8-DIMETHOXYOCTANE

There total 10 articles about 1,8-DIMETHOXYOCTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.2%

methanol (67-56-1) + 1,8-bis(p-toluenesulfonyloxy)octane (36247-32-2) → 1,8-dimethoxyoctane (51306-09-3)

Guidance literature:

With sodium methylate; Heating;

DOI:10.1021/jo00027a014

Reference yield:

1c,8c-dimethoxy-octa-1,3c,5c,7-tetraene (90926-04-8) → 1,8-dimethoxyoctane (51306-09-3)

Guidance literature:

With quinoline; hydrogen; nickel; at 150 ℃; under 36775.4 - 147102 Torr;

Reference yield:

1,8-Octanediol (629-41-4) → 1,8-dimethoxyoctane (51306-09-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 90.9 percent / pyridine / CH₂Cl₂ / 0.33 h / 5 - 15 °C

2: 65.2 percent / NaOMe / Heating

With pyridine; sodium methylate; In dichloromethane;

DOI:10.1021/jo00027a014

upstream raw materials:

1,8-dibromooctane

sodium methylate

1-methoxy-buten-3-yne

1,8-dimethoxy-octa-1,7-diene-3,5-diyne

Downstream raw materials:

1,8-dibromooctane