3,3'-Dihydroxybenzidine

Base Information

• Chemical Name: 3,3'-Dihydroxybenzidine
• CAS No.: 2373-98-0
• Molecular Formula: C12H12 N2 O2
• Molecular Weight: 216.239
• Hs Code.: 29222990
• European Community (EC) Number: 679-800-2
• UNII: OJ61P3RD7H
• DSSTox Substance ID: DTXSID5025073
• Nikkaji Number: J36.114C
• Wikidata: Q27285684
• ChEMBL ID: CHEMBL85811
• Mol file: 2373-98-0.mol

Synonyms:3,3'-DIHYDROXYBENZIDINE;2373-98-0;4,4'-Diamino-[1,1'-biphenyl]-3,3'-diol;4,4'-Diamino-3,3'-biphenyldiol;3,3'-Dihydroxy-4,4'-diaminobiphenyl;3,3'-Dioxybenzidine;4,4'-diaminobiphenyl-3,3'-diol;Benzidine, 3,3'-dihydroxy-;2-amino-5-(4-amino-3-hydroxyphenyl)phenol;3,3'-Dwuoksybenzydyna;3,3-Dihydroxybenzidine;HSDB 4051;m,m'-Biphenol, 6,6'-diamino-;3,3'-Biphenyldiol, 4,4'-diamino-;CCRIS 9225;3,3'-Dihydroxy-4,4'-diamino-biphenyl;3,3'-Dwuoksybenzydyna [Polish];(1,1'-Biphenyl)-3,3'-diol, 4,4'-diamino-;UNII-OJ61P3RD7H;BRN 2725972;OJ61P3RD7H;3,3'-Dihydroxybenzidine (HAB);[1,1'-Biphenyl]-3,3'-diol, 4,4'-diamino-;(1,1'-Biphenyl)-4,4'-diamine, 3,3'-dihydroxy-;MFCD00039149;4,4'-Diamino-3,3'-dihydroxybiphenyl;3-13-00-02309 (Beilstein Handbook Reference);Benzidine-3,3'-diol;5,5'-Bi(2-aminophenol);YSWG019;CHEMBL85811;SCHEMBL105866;DTXSID5025073;ZGDMDBHLKNQPSD-UHFFFAOYSA-;DIHYDROXYBENZIDINE, 3,3'-;AKOS015894243;3,3'-dihydroxy-4,4'-diamino-bipheny;CS-W014847;SB79389;3,3'-DIHYDROXYBENZIDINE [HSDB];NCGC00091520-01;AC-22310;AS-11477;SY052119;4,4'-Diamino[1,1'-biphenyl]-3,3'-diol;D2312;FT-0614060;D71200;4,4'-Diamino[1,1'-biphenyl]-3,3'-diol #;3,3 inverted exclamation mark -Dihydroxybenzidine;A816875;Q27285684;4,4'-Diamino[1,1'-biphenyl]-3,3'-diol, AldrichCPR

Chemical Property of 3,3'-Dihydroxybenzidine

Chemical Property:

• Melting Point: 292 °C
• Refractive Index: 1.6660 (estimate)
• Boiling Point: 440.7°Cat760mmHg
• PKA: 9.15±0.10(Predicted)
• Flash Point: 220.3°C
• PSA: 92.50000
• Density: 1.384g/cm³
• LogP: 3.09160
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Water Solubility.: Practically insoluble in water
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 216.089877630
• Heavy Atom Count: 16
• Complexity: 213

Purity/Quality:

99% ^*data from raw suppliers

3,3''-Dihydroxybenzidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 40-45-48-36/37/38
• Safety Statements: 22-53-45-36/37/39-26-6

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Benzidine and Derivatives
• Canonical SMILES: C1=CC(=C(C=C1C2=CC(=C(C=C2)N)O)O)N
• Uses: 4,4'-diaminobiphenyl-3,3'-diol is used as organic intermediates. 3,3''-Dihydroxybenzidine is used in preparation method of covalent organic framework-based metamaterial for optical device.

Technology Process of 3,3'-Dihydroxybenzidine

There total 16 articles about 3,3'-Dihydroxybenzidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.4%

3,3’-dihydroxy-4,4’-dinitrobiphenyl → 3,3'-dihydroxybenzidine (2373-98-0)

Guidance literature:

With sodium tetrahydroborate; nickel(II) chloride hexahydrate; In tetrahydrofuran; for 2h; Cooling with ice;

Reference yield: 89.9%

C14H8N2O4 → 3,3'-dihydroxybenzidine (2373-98-0)

Guidance literature:

C₁₄H₈N₂O₄; With ammonium hydroxide; at 100 - 110 ℃; under 750.075 - 2250.23 Torr; Large scale;

With sulfuric acid; at 20 - 70 ℃; pH=3-4; Large scale;

Reference yield:

3,3'-dimethoxy-(1,1'-biphenyl)-4,4'-diamine (119-90-4) → 3,3'-dihydroxybenzidine (2373-98-0)

Guidance literature:

With hydrogen iodide; at 138 ℃;

DOI:10.1557/JMR.2000.0220

upstream raw materials:

3,3'-dimethoxy-(1,1'-biphenyl)-4,4'-diamine

4,4'-diamino-3,3'-diethoxybiphenyl

3,3'-bis-sulfooxy-benzidine

hydrogenchloride

Downstream raw materials:

2,2'-diphenyl-6,6'-bibenzoxazole

3,3'-([6,6']bi[benzooxazolyl]-2,2'-diyl)-bis-aniline

4,4'-([6,6']bi[benzooxazolyl]-2,2'-diyl)-bis-aniline

C₂₆H₁₆N₂O₄