9-Amino-N-(2-(dimethylamino)ethyl)-3-methoxy-4-acridinecarboxamide

Base Information

Chemical Name:9-Amino-N-(2-(dimethylamino)ethyl)-3-methoxy-4-acridinecarboxamide
CAS No.:100113-21-1
Molecular Formula:C₁₉H₂₂N₄O₂
Molecular Weight:338.409
Hs Code.:
Mol file:100113-21-1.mol

Synonyms:9-Amino-N-(2-(dimethylamino)ethyl)-3-methoxy-4-acridinecarboxamide

Suppliers and Price of 9-Amino-N-(2-(dimethylamino)ethyl)-3-methoxy-4-acridinecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 9-Amino-N-(2-(dimethylamino)ethyl)-3-methoxy-4-acridinecarboxamide

Chemical Property:

Vapor Pressure:3.94E-14mmHg at 25°C
Boiling Point:595.1°Cat760mmHg
Flash Point:313.7°C
PSA：80.48000
Density:1.233g/cm³
LogP:3.24230

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 9-Amino-N-(2-(dimethylamino)ethyl)-3-methoxy-4-acridinecarboxamide

There total 7 articles about 9-Amino-N-(2-(dimethylamino)ethyl)-3-methoxy-4-acridinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 9-Chloro-3-methoxy-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide

: 100113-21-1
9-Amino-3-methoxy-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide

Guidance literature:: With ammonia; In various solvent(s); at 110 - 120 ℃; for 0.25h;
DOI:10.1021/jm00154a008

Reference yield:

: 54166-96-0
methyl 2-amino-6-methoxybenzoate

: 100113-21-1
9-Amino-3-methoxy-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide

Guidance literature:: Multi-step reaction with 6 steps

1: cupric acetate / dimethylformamide / 12 h / 90 °C

2: polyphosphate ester (PPE) / 1 h / 100 °C

3: 2 N ethanol. NaOH / 0.5 h / Heating

4: SOCl₂ / 1 h / Heating

5: CH₂Cl₂ / 0.5 h / 20 °C

6: NH₃(g) / various solvent(s) / 0.25 h / 110 - 120 °C

With sodium hydroxide; thionyl chloride; polyphosphate ester; ammonia; copper diacetate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00154a008

Reference yield:

: 1488-42-2,109545-72-4
Diphenyliodonium-2-carboxylate

: 100113-21-1
9-Amino-3-methoxy-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide

Guidance literature:: Multi-step reaction with 6 steps

1: cupric acetate / dimethylformamide / 12 h / 90 °C

2: polyphosphate ester (PPE) / 1 h / 100 °C

3: 2 N ethanol. NaOH / 0.5 h / Heating

4: SOCl₂ / 1 h / Heating

5: CH₂Cl₂ / 0.5 h / 20 °C

6: NH₃(g) / various solvent(s) / 0.25 h / 110 - 120 °C

With sodium hydroxide; thionyl chloride; polyphosphate ester; ammonia; copper diacetate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00154a008