Methyl 2-bromo-5-methoxy-3-methylbenzoate

Base Information

Chemical Name:Methyl 2-bromo-5-methoxy-3-methylbenzoate
CAS No.:94742-92-4
Molecular Formula:C10H11BrO3
Molecular Weight:259.09700
Hs Code.:
DSSTox Substance ID:DTXSID00478129
Wikidata:Q82311327

Synonyms:94742-92-4;Methyl 2-bromo-5-methoxy-3-methylbenzoate;Benzoic acid, 2-bromo-5-methoxy-3-methyl-, methyl ester;SCHEMBL17694369;DTXSID00478129;Methyl2-bromo-5-methoxy-3-methylbenzoate

Suppliers and Price of Methyl 2-bromo-5-methoxy-3-methylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl2-bromo-5-methoxy-3-methylbenzoate 97%
1g
$ 681.00

Alichem
Methyl2-bromo-5-methoxy-3-methylbenzoate
1g
$ 701.76

Total 0 raw suppliers

Chemical Property of Methyl 2-bromo-5-methoxy-3-methylbenzoate

Chemical Property:

PSA：35.53000
LogP:2.55270
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:257.98916
Heavy Atom Count:14
Complexity:208

Purity/Quality:: Methyl2-bromo-5-methoxy-3-methylbenzoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1Br)C(=O)OC)OC

Technology Process of Methyl 2-bromo-5-methoxy-3-methylbenzoate

There total 9 articles about Methyl 2-bromo-5-methoxy-3-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 94742-89-9
methyl 6-bromo-3-hydroxy-5-methylbenzoate

: 77-78-1
dimethyl sulfate

: 94742-92-4
methyl 2-bromo-5-methoxy-3-methylbenzoate

Guidance literature:: With potassium carbonate; In acetone; for 1.5h; Heating;

Reference yield:

: 874-63-5
3,5-dimethylmethoxybenzene

: 94742-92-4
methyl 2-bromo-5-methoxy-3-methylbenzoate

Guidance literature:: Multi-step reaction with 6 steps

1: 85 percent / bromine / CCl₄ / -5 °C

2: 92 percent / NBS; AIBN / CCl₄ / 4 h / Heating

3: 95 percent / aq. calcium carbonate / dioxane / 10 h / Heating

4: 85 percent / aq. KMnO₄ / acetone / 0.5 h / Heating

5: thionyl chloride / 3 h / Heating

6: 8.8 g / pyridine / 2 h / 20 °C

With pyridine; potassium permanganate; N-Bromosuccinimide; thionyl chloride; 2,2'-azobis(isobutyronitrile); bromine; calcium carbonate; In 1,4-dioxane; tetrachloromethane; acetone;
DOI:10.1002/chem.200400035

Reference yield:

: 6267-34-1
2-bromo-5-methoxy-1,3-dimethyl-benzene

: 94742-92-4
methyl 2-bromo-5-methoxy-3-methylbenzoate

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / NBS; AIBN / CCl₄ / 4 h / Heating

2: 95 percent / aq. calcium carbonate / dioxane / 10 h / Heating

3: 85 percent / aq. KMnO₄ / acetone / 0.5 h / Heating

4: thionyl chloride / 3 h / Heating

5: 8.8 g / pyridine / 2 h / 20 °C

With pyridine; potassium permanganate; N-Bromosuccinimide; thionyl chloride; 2,2'-azobis(isobutyronitrile); calcium carbonate; In 1,4-dioxane; tetrachloromethane; acetone;
DOI:10.1002/chem.200400035