6-(4-Methoxyphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:6-(4-Methoxyphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
CAS No.:94937-24-3
Molecular Formula:C13H14N2O3
Molecular Weight:246.266
Hs Code.:
DSSTox Substance ID:DTXSID90555852
Nikkaji Number:J2.745.527A
Wikidata:Q82437279

Synonyms:94937-24-3;6-(4-Methoxyphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione;SCHEMBL10569299;DTXSID90555852;GSEOPLSGDIWYPG-UHFFFAOYSA-N;1,3-dimethyl-6-(4-methoxyphenyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

Suppliers and Price of 6-(4-Methoxyphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-(4-Methoxyphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:246.10044231
Heavy Atom Count:18
Complexity:384

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=CC(=O)N(C1=O)C)C2=CC=C(C=C2)OC

Technology Process of 6-(4-Methoxyphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

There total 10 articles about 6-(4-Methoxyphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 696-62-8
para-iodoanisole

: C₁₂H₁₄N₄O₄Zn

: 94937-24-3
1,3-dimethyl-6-(4-methoxyphenyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

Guidance literature:: With trifuran-2-yl-phosphane; bis(dibenzylideneacetone)-palladium⁽⁰⁾; at 25 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.orglett.6b00190

Reference yield: 82.0%

: 874-14-6,156398-76-4
1,3-dimethyluracil

: 5720-07-0
4-methoxyphenylboronic acid

: 94937-24-3
1,3-dimethyl-6-(4-methoxyphenyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

Guidance literature:: With 1,10-Phenanthroline; oxygen; palladium diacetate; In N,N-dimethyl-formamide; at 90 ℃; for 16h; regioselective reaction;
DOI:10.1016/j.tetlet.2013.12.092

Reference yield: 65.0%

: 104-92-7
1-bromo-4-methoxy-benzene

: 874-14-6,156398-76-4
1,3-dimethyluracil

: 94937-24-3
1,3-dimethyl-6-(4-methoxyphenyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

: 105202-42-4
5-(4-methoxyphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

Guidance literature:: With tetrabutyl-ammonium chloride; palladium diacetate; potassium carbonate; Trimethylacetic acid; In N,N-dimethyl-formamide; at 130 ℃; for 12h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.09.066