3659-97-0

Usage

Uses

Used in Pharmaceutical Industry:
1-Methylparabanic acid is used as a reagent in the synthesis of various organic compounds and pharmaceuticals for its wide range of industrial and scientific uses.
Used in Organic Compounds Production:
1-Methylparabanic acid is used as a reagent in the production of various organic compounds due to its versatile chemical properties.
Used as Antiseptic and Disinfectant:
1-Methylparabanic acid is used for its potent antiseptic and disinfectant properties, making it valuable in various fields.
Used in Therapeutic Applications:
1-Methylparabanic acid is studied for its potential therapeutic applications in the treatment of various diseases and health conditions, showcasing its potential as a promising pharmaceutical candidate.

InChI:InChI=1/C4H4N2O3/c1-6-3(8)2(7)5-4(6)9/h1H3,(H,5,7,9)

Upstream product

• 861071-55-8 N,N'-bis-methylcarbamoyl-oxalamide 
• 64-19-7 acetic acid 
• 79-37-8 oxalyl dichloride 
• 60-29-7 diethyl ether 
• 598-50-5 N-Methylurea 
• 19036-49-8 N-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)acetamide 
• 58-08-2 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione 
• 100422-34-2 theobromuric acid 
• 98335-22-9 3,7-dimethyl-1,3,6,7-tetrahydro-purin-2-one 
• 7664-93-9 sulfuric acid 
• 7647-01-0 hydrogenchloride 
• 34356-73-5 2-amino-1-methyl-1H-imidazole-4,5-dione-5-oxime 
• 5213-49-0 2,4-dinitro-1H-imidazole 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 144-62-7 oxalic acid 
• 598-50-5 N-Methylurea 
• 4224-00-4 3-methyl-5,5-diphenyl-imidazolidine-2,4-dione 
• 6843-45-4 1-methylhydantoin 
• 74-89-5 methylamine 
• 3299-64-7 N,N'-dicyclohexyloxamide 
• 14040-79-0 N¹, N²-diphenethyloxalamide 
• 67867-43-0 methyl-phenethyl-imidazolidinetrione 
• 16935-46-9 methyl-phenyl-imidazolidinetrione 
• 956325-62-5 4-({[(methylamino)carbonyl]amino}methyl)benzoic acid 
• 1207374-48-8 1-[(3-phenylimidazolidine-2,4,5-trionyl)methyl]-3-methyl-imidazolidine-2,4,5-trione 
• 110189-06-5 naamidine A 
• 1280726-71-7 5-benzylamino-3-methylimidazole-2,4-dione 
• 1280726-73-9 5-(4-methoxybenzyl)amino-3-methylimidazole-2,4-dione 

Relevant academic research and scientific papers

Study of the methylation reaction of 2,4-dinitroimidazole and potassium 2,4,5-trinitroimidazol-1-ide with dimethyl sulfate

[Figure not available: see fulltext.] The methylation of 2,4-dinitroimidazole and potassium salt of 2,4,5-trinitroimidazole with dimethyl sulfate was reinvestigated. When the reaction system contained a weak base, the reaction products were 1-methyl-2,4-dinitroimidazole and 1-methyl-2,4,5-trinitroimidazole, respectively. However, in the absence of a base in the reaction system, the products contained oxidation byproducts 1-methylimidazolidine-2,4,5-trione, 1,3-dimethylimidazolidine-2,4,5-trione and recovered starting materials. All products were characterized using FT-IR, NMR, and elemental analysis. The structure of 1-methylimidazolidine-2,4,5-trione and 1,3-dimethylimidazolidine-2,4,5-trione were further confirmed by single crystal X-ray diffraction.

5,5′-bipyridyl-2,4,6,2′,4′,6′-hexaone derivatives (hydurilic acids): Syntheses, mechanism of C-C-Bond formation and properties of the dimeric barbituric acid derivatives

A series of hydurilic acid derivatives (5,5′-bipyrimidinyl-2,4,6,2′,4′,6′-hexaones) including several new derivatives was synthesized from 5,6-diaminouracils. Mechanisms for their formation are proposed and discussed. Furthermore, a new method for the preparation of pyrimidine-2,4,5,6-tetraone-5-oxime derivatives (violuric acids) was found starting from 5-amino-6-nitrosouracils.

Ozonolysis of Uracils in Water

The ozonolysis of uracils unsubstituted at the 1-position gave new 1-acyl-5-hydroxyhydantoins and 5-hydroxyhydantoins in water, while that of 1-substituted uracils gave the corresponding 5-hydroxyhydantoins in low yields.The structure of 1-acetyl-5-hydroxy-5-methylhydantoin was determined by X-ray crystallography.

2-Amino-1-methyl-1H-imidazole-4,5-dione: Synthesis and the Dimroth Type Rearrangement to Creatone (2-Methyl-amino-1H-imidazole-4,5-dione)

Treatment of creatinine with BOC-ON gave 2-t-butoxycarbonylamino-1-methyl-1,5-dihydro-4H-imidazol-4-one, which was oxidized with mercury(II) acetate to the corresponding 1H-imidazole-4,5-dione.Deprotection of the amino group of this dione afforded the title compound 4, which in turns was shown to undergo a facile, Dimroth-type rearrangement under weakly acidic conditions to give creatone, thus proving 4 to be the key intermediate in the formation of creatone from various starting materials.The equilibria among these compounds are discussed.

THE STRUCTURE OF THEOBROMURIC ACID

The structure of theobromuric acid was revised and the correct 8a-hydroxy-1,2,3,4,6,7,8,8a-octahydro-1,7-dimethyl-2,4,6,8-tetraoxoimidazo -1,3,5-triazine (5a) formula was assigned on the basis of chemical and spectroscopic evidence.