3-Bromo-3-(4-methoxyphenyl)-3H-diazirine

Base Information

Chemical Name:3-Bromo-3-(4-methoxyphenyl)-3H-diazirine
CAS No.:95911-61-8
Molecular Formula:C8H7BrN2O
Molecular Weight:227.06
Hs Code.:
DSSTox Substance ID:DTXSID40471058
Nikkaji Number:J1.858.839K
Mol file:95911-61-8.mol

Synonyms:95911-61-8;3-Bromo-3-(4-methoxyphenyl)-3H-diazirine;3H-Diazirine, 3-bromo-3-(4-methoxyphenyl)-;DTXSID40471058

Suppliers and Price of 3-Bromo-3-(4-methoxyphenyl)-3H-diazirine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Bromo-3-(4-methoxyphenyl)-3H-diazirine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:225.97418
Heavy Atom Count:12
Complexity:193

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2(N=N2)Br

Technology Process of 3-Bromo-3-(4-methoxyphenyl)-3H-diazirine

There total 5 articles about 3-Bromo-3-(4-methoxyphenyl)-3H-diazirine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 51721-68-7
4-methoxybenzamidine hydrochloride

: 95911-61-8
3-Bromo-3-(4-methoxy-phenyl)-3H-diazirine

Guidance literature:: With sodium hypobromide; lithium bromide; In dimethyl sulfoxide; for 1h;
DOI:10.1021/ja00295a029

Reference yield:

: 874-90-8
4-methoxybenzonitrile

: 95911-61-8
3-Bromo-3-(4-methoxy-phenyl)-3H-diazirine

Guidance literature:: Multi-step reaction with 2 steps

1: 20 percent / 1.) sodium methoxide; 2.) NH₄Cl / methanol / 25 °C / 1.) 48 h; 2.) 24 h

2: 34 percent / NaOBr, LiBr / dimethylsulfoxide / 1 h

With sodium hypobromide; sodium methylate; ammonium chloride; lithium bromide; In methanol; dimethyl sulfoxide;
DOI:10.1021/ja00295a029

Reference yield:

: 4222-26-8
3-chloro-3-(4-methoxyphenyl)diaziridine

: 95911-61-8
3-Bromo-3-(4-methoxy-phenyl)-3H-diazirine

Guidance literature:: Multi-step reaction with 3 steps

1: n-tetrabutylammonium azide / acetonitrile / 24 h / 25.5 °C / in the dark; var. time

2: 20 percent / 1.) sodium methoxide; 2.) NH₄Cl / methanol / 25 °C / 1.) 48 h; 2.) 24 h

3: 34 percent / NaOBr, LiBr / dimethylsulfoxide / 1 h

With sodium hypobromide; sodium methylate; tetrabutylammoniun azide; ammonium chloride; lithium bromide; In methanol; dimethyl sulfoxide; acetonitrile;
DOI:10.1021/ja00295a029