Technology Process of 7-Indolizinol, octahydro-6-(4-methoxyphenyl)-
There total 6 articles about 7-Indolizinol, octahydro-6-(4-methoxyphenyl)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 15h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 70 percent / toluene / 4 h / Heating
2: 82 percent / H2 / 5percent Pd/C / methanol / 24 h
3: 2.) saturated methanolic ammonia / 1.) toluene, reflux, 5 h, 2.) methanol, RT, overnight
4: 72 percent / Collins reagent / CH2Cl2 / 3 h / Ambient temperature
5: 36 percent / aluminium t-butoxide / xylene / 10 h / Heating
6: 10 percent / LiAlH4 / tetrahydrofuran / 15 h / Ambient temperature
With
lithium aluminium tetrahydride; Collins oxidation agent; ammonia; hydrogen; aluminum tri-tert-butoxide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane; toluene; xylene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 82 percent / H2 / 5percent Pd/C / methanol / 24 h
2: 2.) saturated methanolic ammonia / 1.) toluene, reflux, 5 h, 2.) methanol, RT, overnight
3: 72 percent / Collins reagent / CH2Cl2 / 3 h / Ambient temperature
4: 36 percent / aluminium t-butoxide / xylene / 10 h / Heating
5: 10 percent / LiAlH4 / tetrahydrofuran / 15 h / Ambient temperature
With
lithium aluminium tetrahydride; Collins oxidation agent; ammonia; hydrogen; aluminum tri-tert-butoxide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane; xylene;
