2',3'-Dimethoxyflavanone

Base Information

• Chemical Name: 2',3'-Dimethoxyflavanone
• CAS No.: 97207-23-3
• Molecular Formula: C17H16O4
• Molecular Weight: 284.312
• DSSTox Substance ID: DTXSID50398045
• Nikkaji Number: J2.048.095E
• Metabolomics Workbench ID: 74376
• Mol file: 97207-23-3.mol

Synonyms:2',3'-dimethoxyflavanone

Chemical Property of 2',3'-Dimethoxyflavanone

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 284.10485899
• Heavy Atom Count: 21
• Complexity: 370

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC(=C1OC)C2CC(=O)C3=CC=CC=C3O2

Technology Process of 2',3'-Dimethoxyflavanone

There total 5 articles about 2',3'-Dimethoxyflavanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2'',3''-dimethoxy-2'-hydroxychalcone (42220-80-4) → 2,3-dihydro-2-(2,3-dimethoxyphenyl)chromen-4-one (97207-23-3)

Guidance literature:

With pyridine; In water; at 20 ℃; for 3h;

DOI:10.14233/ajchem.2013.14634

Reference yield: 18.0%

2'',3''-dimethoxy-2'-hydroxychalcone (42220-80-4) → 3'-hydroxy-2'-methoxyflavanone + 2''-methoxy-2',3''-dihydroxychalcone + 2,3-dihydro-2-(2,3-dimethoxyphenyl)chromen-4-one (97207-23-3)

Guidance literature:

With Aspergillus niger LSPN₀₀₁; In ethanol; at 20 ℃; for 120h; Enzymatic reaction;

DOI:10.3109/10242422.2013.813489

Reference yield: 3.0%

(E)-3-(2,3-dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one (34000-33-4,42220-80-4) → (Z)-2(2,3-dimethoxybenzylidene)benzofuran-3(2H)-one (111017-66-4) + 2',3'-Dimethoxyflavone (2554-84-9) + 2,3-dihydro-2-(2,3-dimethoxyphenyl)chromen-4-one (97207-23-3)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; for 72h; Heating;

upstream raw materials:

(E)-3-(2,3-dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one

o-hydroxyacetophenone

2,3-dimethyoxybenzaldehyde

2'',3''-dimethoxy-2'-hydroxychalcone

Downstream raw materials:

2',3'-Dimethoxyflavone