(E)-N-Methyl-2-(acetylamino)-3-phenylacrylamide

Base Information

Chemical Name:(E)-N-Methyl-2-(acetylamino)-3-phenylacrylamide
CAS No.:91566-64-2
Molecular Formula:C₁₂H₁₄N₂O₂
Molecular Weight:218.255
Hs Code.:
NSC Number:168529
Nikkaji Number:J1.235.272G

Synonyms:NSC168529;NSC-168529;(E)-N-Methyl-2-(acetylamino)-3-phenylacrylamide;91566-64-2

Suppliers and Price of (E)-N-Methyl-2-(acetylamino)-3-phenylacrylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (E)-N-Methyl-2-(acetylamino)-3-phenylacrylamide

Chemical Property:

Vapor Pressure:5.27E-11mmHg at 25°C
Boiling Point:522.3°Cat760mmHg
Flash Point:225.4°C
Density:1.139g/cm³
XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:218.105527694
Heavy Atom Count:16
Complexity:291

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(=CC1=CC=CC=C1)C(=O)NC
Isomeric SMILES:CC(=O)N/C(=C/C1=CC=CC=C1)/C(=O)NC

Technology Process of (E)-N-Methyl-2-(acetylamino)-3-phenylacrylamide

There total 3 articles about (E)-N-Methyl-2-(acetylamino)-3-phenylacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 881-90-3
4-benzylidene-2-methyl-2-oxazolin-5-one

: 74-89-5
methylamine

: 81307-03-1,91566-64-2
N-methyl-2-(acetamido)-3-phenylacrylamide

Guidance literature:: In ethanol; water; at 20 ℃; for 0.5h;
DOI:10.1016/j.tet.2012.04.102

Reference yield:

: 100-52-7
benzaldehyde

: 81307-03-1,91566-64-2
N-methyl-2-(acetamido)-3-phenylacrylamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium acetate; acetic anhydride / 4 h / 95 - 135 °C

2: ethanol; water / 0.5 h / 20 °C

With sodium acetate; acetic anhydride; In ethanol; water; 1: Erlenmeyer azlactone synthesis;
DOI:10.1016/j.tet.2012.04.102