2-Chloro-5,5-dimethyl-4-phenyl-1,3,2lambda~5~-dioxaphosphinan-2-one

Base Information

Chemical Name:2-Chloro-5,5-dimethyl-4-phenyl-1,3,2lambda~5~-dioxaphosphinan-2-one
CAS No.:98675-02-6
Molecular Formula:C11H14ClO3P
Molecular Weight:260.657
Hs Code.:
DSSTox Substance ID:DTXSID60542577
Nikkaji Number:J1.032.331B,J2.365.678G

Synonyms:98675-02-6;SCHEMBL18548536;DTXSID60542577;2-Chloro-5,5-dimethyl-4-phenyl-1,3,2lambda~5~-dioxaphosphinan-2-one

Suppliers and Price of 2-Chloro-5,5-dimethyl-4-phenyl-1,3,2lambda~5~-dioxaphosphinan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Chloro-5,5-dimethyl-4-phenyl-1,3,2lambda~5~-dioxaphosphinan-2-one

Chemical Property:

PSA：45.34000
LogP:4.14760
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:260.0369090
Heavy Atom Count:16
Complexity:300

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(COP(=O)(OC1C2=CC=CC=C2)Cl)C

Technology Process of 2-Chloro-5,5-dimethyl-4-phenyl-1,3,2lambda~5~-dioxaphosphinan-2-one

There total 3 articles about 2-Chloro-5,5-dimethyl-4-phenyl-1,3,2lambda~5~-dioxaphosphinan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 33950-46-8,98674-79-4
1-phenyl-2,2-dimethyl-1,3-propanediol

: 98675-02-6
2-chloro-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinane 2-oxide

Guidance literature:: With triethylamine; trichlorophosphate; In dichloromethane; for 3h; Heating;
DOI:10.1021/jo00223a018

Reference yield:

: 100-52-7
benzaldehyde

: 98675-02-6
2-chloro-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinane 2-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / KOH / ethanol / 5 h / 50 - 60 °C

2: POCl₃, triethylamine / CH₂Cl₂ / 3 h / Heating

With potassium hydroxide; triethylamine; trichlorophosphate; In ethanol; dichloromethane;
DOI:10.1021/jo00223a018

Reference yield:

: 100-52-7
benzaldehyde

: 98675-02-6
2-chloro-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinane 2-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / ethanol / 5 h / 50 - 60 °C

2: POCl₃ / CH₂Cl₂ / 2 h / Heating

With potassium hydroxide; trichlorophosphate; In ethanol; dichloromethane;
DOI:10.1080/104265090968343