2-Naphthalenecarboxylic acid, 2-amino-1,2,3,4-tetrahydro-5,8-dimethoxy-, methyl ester, (R)-

Base Information

Chemical Name:2-Naphthalenecarboxylic acid, 2-amino-1,2,3,4-tetrahydro-5,8-dimethoxy-, methyl ester, (R)-
CAS No.:99907-83-2
Molecular Formula:C14H19NO4
Molecular Weight:265.30500
Hs Code.:

Synonyms:(R)-2-Amino-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester;

Suppliers and Price of 2-Naphthalenecarboxylic acid, 2-amino-1,2,3,4-tetrahydro-5,8-dimethoxy-, methyl ester, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 4 raw suppliers

Chemical Property of 2-Naphthalenecarboxylic acid, 2-amino-1,2,3,4-tetrahydro-5,8-dimethoxy-, methyl ester, (R)-

Chemical Property:

PSA：70.78000
LogP:1.76330

Purity/Quality:: >98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2-Naphthalenecarboxylic acid, 2-amino-1,2,3,4-tetrahydro-5,8-dimethoxy-, methyl ester, (R)-

There total 8 articles about 2-Naphthalenecarboxylic acid, 2-amino-1,2,3,4-tetrahydro-5,8-dimethoxy-, methyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.6%

: 67-56-1
methanol

: (R)-(-)-2-amino-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthoic acid

: 99907-83-2
(R)-(-)-2-amino-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthoic acid methyl ester

Guidance literature:: With hydrogenchloride; In methanol; at 25 ℃; Cooling with ice;

Reference yield:

: 37464-90-7
5,8-dimethoxy-2-tetralone

: 99907-83-2
(R)-(-)-2-amino-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 98.7 percent / ammonium carbonate / ethanol; H₂O / 1 h / Heating

2: 92 percent / barium hydroxide octahydrate / H₂O / 36 h / Heating

3: 94.9 percent / HCl (g) / 24 h / 25 °C

With ammonium carbonate; hydrogenchloride; barium hydroxide octahydrate; In ethanol; water;
DOI:10.1021/jo00229a010

Reference yield:

: 2-Amino-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalene-2-carbonitrile

: 99907-83-2
(R)-(-)-2-amino-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / barium hydroxide octahydrate / H₂O / 36 h / Heating

2: 94.9 percent / HCl (g) / 24 h / 25 °C

With hydrogenchloride; barium hydroxide octahydrate; In water;
DOI:10.1021/jo00229a010