1-Ethyl-3-iodo pyrazole

Base Information

• Chemical Name: 1-Ethyl-3-iodo pyrazole
• CAS No.: 1202781-34-7
• Molecular Formula: C5H7IN2
• Molecular Weight: 222.028
• Hs Code.: 2933199090
• Mol file: 1202781-34-7.mol

Synonyms:1-Ethyl-3-iodo pyrazole;1-Ethyl-3-iodo-1H-pyrazole

Chemical Property of 1-Ethyl-3-iodo pyrazole

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

1-Ethyl-3-iodo-1H-pyrazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Ethyl-3-iodo pyrazole

There total 2 articles about 1-Ethyl-3-iodo pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

ethyl iodide (75-03-6) + 3-iodo-1H-pyrazole (4522-35-4) → 1-ethyl-3-iodo-1H-pyrazole (1202781-34-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 16h;

Reference yield:

→ 1-ethyl-3-iodo-1H-pyrazole (1202781-34-7)

Guidance literature:

Reference yield: 83.3%

1-ethyl-3-iodo-1H-pyrazole (1202781-34-7) + 8-(tert-Butoxycarbonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (138091-52-8) → tert-butyl 3-(1-ethylpyrazol-3-yl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate

Guidance literature:

With copper(l) iodide; potassium carbonate; N,N`-dimethylethylenediamine; In 1,4-dioxane; at 100 ℃; for 14h; Inert atmosphere;

upstream raw materials:

ethyl iodide

3-iodo-1H-pyrazole

Refernces

• 1、 -. "AUTOTAXIN INHIBITORS AND USES THEREOF". Page/Page column 190. . Retrieved 2012/03/11.