1,2,3,4-Tetrahydroquinoline-6-carbonitrile

Base Information

Chemical Name:1,2,3,4-Tetrahydroquinoline-6-carbonitrile
CAS No.:50741-36-1
Molecular Formula:C10H10N2
Molecular Weight:158.203
Hs Code.:2933499090
European Community (EC) Number:851-361-3
DSSTox Substance ID:DTXSID50562764
Nikkaji Number:J306.175B
Wikidata:Q82447035
Mol file:50741-36-1.mol

Synonyms:1,2,3,4-Tetrahydroquinoline-6-carbonitrile;50741-36-1;6-Quinolinecarbonitrile, 1,2,3,4-tetrahydro-;SCHEMBL3116370;DTXSID50562764;YPCHNZDCUARXNN-UHFFFAOYSA-N;MFCD14534464;AKOS022172380;CS-W005904;DS-2997;EN300-221198;A871471;Z1262564947

Suppliers and Price of 1,2,3,4-Tetrahydroquinoline-6-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,2,3,4-tetrahydroquinoline-6-carbonitrile
10mg
$ 45.00

SynQuest Laboratories
1,2,3,4-Tetrahydroquinoline-6-carbonitrile 96%
100 mg
$ 176.00

SynQuest Laboratories
1,2,3,4-Tetrahydroquinoline-6-carbonitrile 96%
250 mg
$ 296.00

SynQuest Laboratories
1,2,3,4-Tetrahydroquinoline-6-carbonitrile 96%
1 g
$ 736.00

Matrix Scientific
1,2,3,4-Tetrahydroquinoline-6-carbonitrile >95%
1g
$ 900.00

Crysdot
1,2,3,4-Tetrahydroquinoline-6-carbonitrile 95%
1g
$ 292.00

Crysdot
1,2,3,4-Tetrahydroquinoline-6-carbonitrile 95%
5g
$ 875.00

Chemenu
1,2,3,4-tetrahydroquinoline-6-carbonitrile 95%
5g
$ 827.00

Chemenu
1,2,3,4-tetrahydroquinoline-6-carbonitrile 95%
1g
$ 276.00

Chemcia Scientific
1,2,3,4-Tetrahydroquinoline-6-carbonitrile ＞96%
0.5 G
$ 195.00

Total 17 raw suppliers

Chemical Property of 1,2,3,4-Tetrahydroquinoline-6-carbonitrile

Chemical Property:

Melting Point:77-79 °C
Boiling Point:322.9±31.0 °C(Predicted)
PKA:1.76±0.20(Predicted)
PSA：35.82000
Density:1.14±0.1 g/cm3(Predicted)
LogP:2.05438
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:158.084398327
Heavy Atom Count:12
Complexity:203

Purity/Quality:

97% ^*data from raw suppliers

1,2,3,4-tetrahydroquinoline-6-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C=CC(=C2)C#N)NC1

Technology Process of 1,2,3,4-Tetrahydroquinoline-6-carbonitrile

There total 7 articles about 1,2,3,4-Tetrahydroquinoline-6-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 23395-72-4
quinoline-6-carbonitrile

: 91-61-2
6-methyl-1,2,3,4 tetrahydroquinoline

: 50741-36-1
1,2,3,4-tetrahydroquinoline-6-carbonitrile

Guidance literature:: With hydrogen; In toluene; at 150 ℃; for 18h; under 9000.9 Torr; regioselective reaction; Autoclave; Sealed tube;
DOI:10.1021/acscatal.7b04260

Reference yield: 80.0%

: 22190-35-8
6-bromo-1,2,3,4-tetrahydroquinoline

: 557-21-1
dicyanozinc

: 50741-36-1
1,2,3,4-tetrahydroquinoline-6-carbonitrile

Guidance literature:: tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 120 ℃; for 2h;

Reference yield: 76.0%

: 23395-72-4
quinoline-6-carbonitrile

: 50741-36-1
1,2,3,4-tetrahydroquinoline-6-carbonitrile

Guidance literature:: With C₄₆H₄₉CoN₃P₄⁽²⁺⁾*2BF₄^(1-); hydrogen; potassium hydroxide; In toluene; acetonitrile; at 100 ℃; for 48h; under 22801.5 Torr; chemoselective reaction; Autoclave; Glovebox;
DOI:10.1021/jacs.9b11070