23395-72-4

Basic information

• Product Name: quinoline-6-carbonitrile
• Synonyms: quinoline-6-carbonitrile;6-Quinolinecarbonitrile;Quinolin-6-carbonitrile
• CAS NO: 23395-72-4
• Molecular Formula: C₁₀H₆N₂
• Molecular Weight: 154.16804
• Mol File: 23395-72-4.mol
• Article Data: 43

Chemical Properties

• Melting Point: 133-134℃ (methanol )
• Boiling Point: 323.7 °C at 760 mmHg
• Flash Point: 115.5 °C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 0.000258mmHg at 25°C
• Refractive Index: 1.654
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.50±0.10(Predicted)
• CAS DataBase Reference: quinoline-6-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: quinoline-6-carbonitrile(23395-72-4)
• EPA Substance Registry System: quinoline-6-carbonitrile(23395-72-4)

Safety Data

• Hazard Codes: T
• Statements: 25-41
• Safety Statements: 26-39-45
• RIDADR: UN 2811 6.1 / PGIII
• Hazardous Substances Data: 23395-72-4(Hazardous Substances Data)

Usage

Uses

6-Cyanoquinoline is used in the preparation of aromatic nitriles.

InChI:InChI=1/C10H6N2/c11-7-8-3-4-10-9(6-8)2-1-5-12-10/h1-6H

Upstream product

• 665033-21-6 3-amino-4-iodobenzonitrile 
• 557-21-1 zinc(II) cyanide 
• 612-57-7 6-chloroquinoline 
• 100516-88-9 6-(hydroxymethyl)quinoline 
• 50741-36-1 1,2,3,4-tetrahydroquinoline-6-carbonitrile 
• 173089-80-0 quinolin-6-yl triflate 
• 4113-04-6 quinoline-6-carbaldehyde 
• 13327-31-6 6-iodoquinoline 
• 77287-34-4 formamide 
• 5332-25-2 6-bromoquinoline 
• 109-74-0 propyl cyanide 
• 773837-37-9 sodium cyanide 
• 5807-02-3 4-morpholinoacetonitrile 
• 115580-96-6 N,N-dimethyl O-(quinolyl-6) carbamate 

Downstream Products

• 99071-54-2 quinolin-6-ylmethanamine 
• 1350426-22-0 6-((5-(4-Methoxyphenyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)methyl)quinoline 
• 1350426-43-5 6-((5-(3-(trifluoromethoxy)phenyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)methyl)quinoline 
• 1350426-45-7 6-((5-(3-(difluoromethoxy)phenyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)methyl)quinoline 
• 1350428-18-0 N-Phenyl-3-(quinolin-6-ylmethyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine 
• 1350428-19-1 6-((5-Phenoxy-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)methyl)quinoline 
• 91-61-2 6-methyl-1,2,3,4 tetrahydroquinoline 
• 50741-36-1 1,2,3,4-tetrahydroquinoline-6-carbonitrile 
• 63124-11-8 2-oxo-1H-quinoline-6-carbonitrile 
• 91-22-5 quinoline 
• 70682-98-3 N-phenylquinolin-6-amine 
• 956907-14-5 6-((6-bromo-1H-[1,2,3]triazolo[4,5-b]pyrazine-1-yl)methyl)quinoline 
• 1459732-45-6 2,6-difluoro-4-(3-(quinolin-6-ylmethyl)-3H-imidazo[4,5-b]pyridin-5-yl)benzoic acid 
• 1459732-44-5 methyl 2,6-difluoro-4-(3-(quinolin-6-ylmethyl)-3H-imidazo[4,5-b]pyridin-5-yl)benzoate 

Relevant articles and documents

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A “universal” catalyst for aerobic oxidations to synthesize (hetero)aromatic aldehydes, ketones, esters, acids, nitriles, and amides

Functionalized (hetero)aromatic compounds are indispensable chemicals widely used in basic and applied sciences. Among these, especially aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides represent valuable fine and bulk chemicals, which are used in chemical, pharmaceutical, agrochemical, and material industries. For their synthesis, catalytic aerobic oxidation of alcohols constitutes a green, sustainable, and cost-effective process, which should ideally make use of active and selective 3D metals. Here, we report the preparation of graphitic layers encapsulated in Co-nanoparticles by pyrolysis of cobalt-piperazine-tartaric acid complex on carbon as a most general oxidation catalyst. This unique material allows for the synthesis of simple, functionalized, and structurally diverse (hetero)aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides from alcohols in excellent yields in the presence of air.

Method for converting aromatic aldehyde into aromatic nitrile by using sulfur powder promoted inorganic ammonium as nitrogen source (by machine translation)

The invention discloses a method for converting aromatic aldehyde into aromatic nitrile. The method is conversion of high yield of aromatic aldehyde one-pot reaction of sulfur powder promoted inorganic ammonium as a nitrogen source into aromatic nitrile. The method has the advantages of no need of metal participation, no need of strong oxide, compatibility of reaction to air, easiness in amplification to a gram scale and the like, and overcomes the problems of harsh reaction conditions, complex operation, low functional group compatibility and the like in the prior art. (by machine translation)