methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate

Base Information

Chemical Name:methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate
CAS No.:872619-43-7
Molecular Formula:C9 H7 BrN2 O2
Molecular Weight:255.071
Hs Code.:2933990090
European Community (EC) Number:836-766-5
DSSTox Substance ID:DTXSID10583298
Wikidata:Q82474843
Mol file:872619-43-7.mol

Synonyms:872619-43-7;methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate;METHYL 5-BROMO-7-AZAINDOLE-3-CARBOXYLATE;1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID, 5-BROMO-, METHYL ESTER;MFCD15529254;SCHEMBL1427263;DTXSID10583298;QFENDXLPFBGAIX-UHFFFAOYSA-N;BCP14339;CS-B0568;XJB61943;AKOS024259803;PB28581;AS-51061;SY098746;EN300-201784;P11816;A862697;methyl5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate;Z1269177953;5-BROMO-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER

Suppliers and Price of methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate
50mg
$ 60.00

SynQuest Laboratories
Methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate 97.0%
1 g
$ 840.00

SynQuest Laboratories
Methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate 97.0%
250 mg
$ 320.00

Crysdot
Methyl5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate 95+%
1g
$ 200.00

Crysdot
Methyl5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate 95+%
100mg
$ 82.00

Crysdot
Methyl5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate 95+%
250mg
$ 116.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,5-bromo-,methylester 96.95%
5g
$ 527.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,5-bromo-,methylester 96.95%
10g
$ 948.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,5-bromo-,methylester 96.95%
250mg
$ 117.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,5-bromo-,methylester 96.95%
100mg
$ 90.00

Total 28 raw suppliers

Chemical Property of methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate

Chemical Property:

PKA:11.33±0.40(Predicted)
PSA：54.98000
Density:1.709±0.06 g/cm3(Predicted)
LogP:2.11200
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:253.96909
Heavy Atom Count:14
Complexity:237

Purity/Quality:

99%, ^*data from raw suppliers

Methyl5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CNC2=C1C=C(C=N2)Br

Technology Process of methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate

There total 4 articles about methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 67-56-1
methanol

: 849068-61-7
5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

: 872619-43-7
5-bromo-1H-pyrrole[2,3-b]pyrimidine-3-carboxylic acid methyl ester

Guidance literature:: With sulfuric acid; for 24h; Reflux;

Reference yield: 84.6%

: (E)-3-((3,5-dibromopyridin-2-yl)imino)propionic acid methyl ester

: 872619-43-7
5-bromo-1H-pyrrole[2,3-b]pyrimidine-3-carboxylic acid methyl ester

Guidance literature:: (E)-3-((3,5-dibromopyridin-2-yl)imino)propionic acid methyl ester; With sodium hydride; In 1,4-dioxane; for 2h; Industrial scale;

With triethylamine; copper(I) bromide; at 80 ℃; for 14h; Industrial scale;

Reference yield: 69.2%

: 67-56-1
methanol

: 76-02-8
trifluoroacetyl chloride

: 183208-35-7
5-bromo-1H-pyrrolo[2,3-b]pyridine

: 872619-43-7
5-bromo-1H-pyrrole[2,3-b]pyrimidine-3-carboxylic acid methyl ester

Guidance literature:: trifluoroacetyl chloride; 5-bromo-1H-pyrrolo[2,3-b]pyridine; With aluminum (III) chloride; In dichloromethane; at 0 - 20 ℃; for 3h;

methanol; With triethylamine; at 65 ℃; for 12h;