4,6-Dichloro-2-(propylthio)pyrimidin-5-amine

Base Information Edit

Chemical Name:4,6-Dichloro-2-(propylthio)pyrimidin-5-amine
CAS No.:145783-15-9
Molecular Formula:C7H9Cl2N3S
Molecular Weight:238.141
Hs Code.:29335990
European Community (EC) Number:808-051-8
UNII:QY0S1U6LEG
DSSTox Substance ID:DTXSID60465838
Wikidata:Q72467777
Mol file:145783-15-9.mol

Synonyms:145783-15-9;4,6-dichloro-2-(propylthio)pyrimidin-5-amine;4,6-dichloro-2-propylthiopyrimidine-5-amine;4,6-DICHLORO-2-(PROPYLSULFANYL)PYRIMIDIN-5-AMINE;5-PYRIMIDINAMINE, 4,6-DICHLORO-2-(PROPYLTHIO)-;5-Amino-4,6-dichloro-2-(propylthio)pyrimidine;4,6-dichloro-2-propylsulfanylpyrimidin-5-amine;QY0S1U6LEG;MFCD16875503;4,6-Dichloro-2-(propylthio) pyrimidine-5-amine;4,6-Dichloro-2-(propylthio)-5-pyrimidinamine;4,6-Dichloro-2-(propylthio)pyrimidin-5-amine;UNII-QY0S1U6LEG;4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine;SCHEMBL595428;DTXSID60465838;CJJLJBFJNXMANZ-UHFFFAOYSA-N;BCP20990;CS-M1848;AKOS015851287;EX-7178;GS-5899;PB24255;AC-26815;BP-20662;SY023636;5-amino-4,6-dichloro-2-propylthiopyrimidine;AM20090748;FT-0686722;4,6-Dichloro-2-propylthio-pyrimidine-5-amine;EN300-2953109;A846829;J-514127;4,6-Dichloro-2-propylthiopyrimidine-5-amine, AldrichCPR;Ticagrelor, Ticagrelor Intermediates, CAS:145783-15-9, 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine

Suppliers and Price of 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
5-Amino-4,6-dichloro-2-(propylthio)pyrimidine >98.0%(GC)
1g
$ 61.00

TCI Chemical
5-Amino-4,6-dichloro-2-(propylthio)pyrimidine >98.0%(GC)
5g
$ 183.00

SynQuest Laboratories
4,6-Dichloro-2-(propylsulfanyl)pyrimidin-5-amine 97.0%
25 g
$ 105.00

SynQuest Laboratories
4,6-Dichloro-2-(propylsulfanyl)pyrimidin-5-amine 97.0%
100 g
$ 260.00

SynQuest Laboratories
4,6-Dichloro-2-(propylsulfanyl)pyrimidin-5-amine 97.0%
5 g
$ 80.00

SynQuest Laboratories
4,6-Dichloro-2-(propylsulfanyl)pyrimidin-5-amine 97.0%
500 g
$ 625.00

Matrix Scientific
4,6-Dichloro-2-(propylthio)pyrimidin-5-amine 95+%
1g
$ 706.00

Matrix Scientific
4,6-Dichloro-2-(propylthio)pyrimidin-5-amine 95+%
250mg
$ 319.00

Crysdot
4,6-Dichloro-2-(propylthio)pyrimidin-5-amine 98%
500g
$ 371.00

Chem-Impex
5-Amino-4,6-dichloro-2-(propylthio)pyrimidine,≥98%(GC) ≥98%(GC)
1G
$ 72.19

Total 190 raw suppliers

Chemical Property of 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.615
Boiling Point:334.05 °C at 760 mmHg
PKA:-3.46±0.12(Predicted)
Flash Point:155.828 °C
PSA：77.10000
Density:1.445 g/cm³
LogP:3.44890
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:soluble in Methanol
Water Solubility.:100mg/L at 22℃
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:236.9894239
Heavy Atom Count:13
Complexity:149

Purity/Quality:

99% ^*data from raw suppliers

5-Amino-4,6-dichloro-2-(propylthio)pyrimidine >98.0%(GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:

Useful:

Canonical SMILES:CCCSC1=NC(=C(C(=N1)Cl)N)Cl
Uses Intermediate in the preparation of Ticagrelor (T437700) and reversible P2Y12 receptor antagonists.

Technology Process of 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine

There total 16 articles about 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 145783-14-8
4,6-dichloro-5-nitro-2-(propylsulfanyl)pyrimidine

: 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine

Guidance literature:: With ammonium molibdate; hydrogen; hypophosphorous acid; platinum on carbon; In tert-butyl methyl ether; at 20 - 65 ℃; for 7h; under 7500.75 Torr; Product distribution / selectivity; Inert atmosphere;