Methyl (4-methoxy-2-methylphenyl)acetate

Base Information

• Chemical Name: Methyl (4-methoxy-2-methylphenyl)acetate
• CAS No.: 30888-94-9
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• DSSTox Substance ID: DTXSID20553700
• Wikidata: Q72490326
• Mol file: 30888-94-9.mol

Synonyms:Methyl (4-methoxy-2-methylphenyl)acetate;30888-94-9;METHYL 2-(4-METHOXY-2-METHYLPHENYL)ACETATE;SCHEMBL3918324;DTXSID20553700;XXTWNWQHEGVDMQ-UHFFFAOYSA-N;AKOS002392953;(4-Methoxy-2-methyl-phenyl)-acetic acid methyl ester

Chemical Property of Methyl (4-methoxy-2-methylphenyl)acetate

Chemical Property:

• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.5
• Boiling Point: 279.565°C at 760 mmHg
• Flash Point: 112.236°C
• PSA: 35.53000
• Density: 1.064g/cm³
• LogP: 1.71910
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 194.094294304
• Heavy Atom Count: 14
• Complexity: 191

Purity/Quality:

99%,98%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)OC)CC(=O)OC

Technology Process of Methyl (4-methoxy-2-methylphenyl)acetate

There total 5 articles about Methyl (4-methoxy-2-methylphenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) → methyl 2-(4-methoxy-2-methylphenyl)acetate (30888-94-9)

Guidance literature:

4-methoxy-2-methylbenzoic acid; With thionyl chloride; for 2h; Heating / reflux;

diazomethane; With silver benzoate; triethylamine; In methanol; diethyl ether; toluene; at 0 - 60 ℃; for 19h;

Reference yield:

1-diazo-2-(4-methoxy-2-methylphenyl)ethan-2-one (114474-03-2) → methyl 2-(4-methoxy-2-methylphenyl)acetate (30888-94-9)

Guidance literature:

With silver benzoate; triethylamine; In methanol; at 60 ℃; for 1h; Heating / reflux;

Reference yield:

methanol (67-56-1) + 1-diazo-2-(4-methoxy-2-methylphenyl)ethan-2-one (114474-03-2) → methyl 2-(4-methoxy-2-methylphenyl)acetate (30888-94-9)

Guidance literature:

With silver benzoate; triethylamine; at 60 ℃; for 1h;

upstream raw materials:

4-methoxy-2-methylphenylacetic acid

methanol

1-(4-methoxy-2-methylphenyl)ethanone

diazomethane

Downstream raw materials:

2-(4-methoxy-2-methylphenyl)ethanol

4-hydroxy-2-methylphenylacetic acid methyl ester