1-(4-Methoxy-2-methylphenyl)ethanone

Base Information

• Chemical Name: 1-(4-Methoxy-2-methylphenyl)ethanone
• CAS No.: 24826-74-2
• Molecular Formula: C10H12 O2
• Molecular Weight: 164.204
• Hs Code.: 2914390090
• European Community (EC) Number: 831-612-3
• DSSTox Substance ID: DTXSID30415840
• Nikkaji Number: J1.908.554F
• Wikidata: Q82224866
• Mol file: 24826-74-2.mol

Synonyms:1-(4-methoxy-2-methylphenyl)ethanone;24826-74-2;1-(4-methoxy-2-methylphenyl)ethan-1-one;4'-methoxy-2'-methylacetophenone;Ethanone, 1-(4-methoxy-2-methylphenyl)-;1-(4-Methoxy-2-methyl-phenyl)-ethanone;4-methoxy-2-methylacetophenone;SCHEMBL1539315;4-Methoxy-2-methyl acetophenone;DTXSID30415840;2'-methyl-4'-methoxyacetophenone;ZUQDIVXHYQNBKJ-UHFFFAOYSA-N;AKOS000112426;CS-16825;CS-0105511;FT-0724436;EN300-99708;D76545;Z285137066;InChI=1/C10H12O2/c1-7-6-9(12-3)4-5-10(7)8(2)11/h4-6H,1-3H

Chemical Property of 1-(4-Methoxy-2-methylphenyl)ethanone

Chemical Property:

• Melting Point: 116.5°C
• Boiling Point: 267 °C(Press: 735 Torr)
• PSA: 26.30000
• Density: 1.0796 g/cm3
• LogP: 2.20620
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 164.083729621
• Heavy Atom Count: 12
• Complexity: 165

Purity/Quality:

99% ^*data from raw suppliers

1-(4-Methoxy-2-methylphenyl)ethanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)OC)C(=O)C

Technology Process of 1-(4-Methoxy-2-methylphenyl)ethanone

There total 23 articles about 1-(4-Methoxy-2-methylphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4'-hydroxy-2'methylacetophenone (875-59-2) + methyl iodide (74-88-4) → 1-(4-methoxy-2-methylphenyl)ethanone (24826-74-2)

Guidance literature:

With potassium carbonate; In acetone; Heating;

DOI:10.1021/jo00063a049

Reference yield: 98.0%

1-ethynyl-4-methoxy-2-methylbenzene (74331-69-4) → 1-(4-methoxy-2-methylphenyl)ethanone (24826-74-2)

Guidance literature:

With tetrafluoroboric acid; In chloroform-d1; water; at 60 ℃; for 1h; Reagent/catalyst; Time;

DOI:10.1039/c6cy00307a

Reference yield: 93.0%

→ 1-(4-methoxy-2-methylphenyl)ethanone (24826-74-2)

Guidance literature:

With potassium carbonate; In [⁽²⁾H₆]acetone; at 23 ℃; for 1h;

In acetone; at 23 ℃; for 15h;

upstream raw materials:

acetic anhydride

acetyl chloride

1-methoxy-3-methyl-benzene

4'-hydroxy-2'methylacetophenone

Downstream raw materials:

1-(4-methoxy-2-methyl-phenyl)-ethanone oxime

1-(4-methoxy-2-methyl-3,5-dinitro-phenyl)-ethanone

2,3-bis-(4-methoxy-2-methyl-phenyl)-butane-2,3-diol

methyl 2-(4-methoxy-2-methylphenyl)acetate