(2-Benzyl-1,2,3,4-tetrahydroisoquinolin-1-YL)methanamine

Base Information

Chemical Name:(2-Benzyl-1,2,3,4-tetrahydroisoquinolin-1-YL)methanamine
CAS No.:40615-06-3
Molecular Formula:C17H20N2
Molecular Weight:252.359
Hs Code.:2933499090
DSSTox Substance ID:DTXSID601181362
Wikidata:Q107947468
Mol file:40615-06-3.mol

Synonyms:40615-06-3;(2-BENZYL-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)METHANAMINE;SCHEMBL9815275;RZFAFCKRZOXRGI-UHFFFAOYSA-N;DTXSID601181362;(2-Benzyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methanamine 95+%;AKOS015904191;FT-0724589;1-aminomethyl-2-benzyl-1,2,3,4-tetrahydroisoquinoline;1,2,3,4-Tetrahydro-2-(phenylmethyl)-1-isoquinolinemethanamine

Suppliers and Price of (2-Benzyl-1,2,3,4-tetrahydroisoquinolin-1-YL)methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(2-BENZYL-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)METHANAMINE 95.00%
5MG
$ 496.66

Total 6 raw suppliers

Chemical Property of (2-Benzyl-1,2,3,4-tetrahydroisoquinolin-1-YL)methanamine

Chemical Property:

Vapor Pressure:4.36E-06mmHg at 25°C
Boiling Point:383.6°C at 760 mmHg
Flash Point:168.9°C
PSA：29.26000
Density:1.095g/cm³
LogP:3.38290
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:252.162648646
Heavy Atom Count:19
Complexity:272

Purity/Quality:

99% ^*data from raw suppliers

(2-BENZYL-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)METHANAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C(C2=CC=CC=C21)CN)CC3=CC=CC=C3

Technology Process of (2-Benzyl-1,2,3,4-tetrahydroisoquinolin-1-YL)methanamine

There total 6 articles about (2-Benzyl-1,2,3,4-tetrahydroisoquinolin-1-YL)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 37039-47-7
2-benzyl-1-cyano-1,2,3,4-tetrahydroisoquinoline bromide

: 40615-06-3
(2-benzyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methanamine

Guidance literature:: With aluminium hydride; In diethyl ether;
DOI:10.1021/jm00358a010

Reference yield:

: 22901-09-3
2-(2-bromoethyl)benzaldehyde

: 40615-06-3
(2-benzyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methanamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: indium(III) triflate / chloroform / 20 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: Ν,Ν-dimethylethylamine alane / diethyl ether / 12.5 h / 0 - 20 °C

With indium(III) triflate; Ν,Ν-dimethylethylamine alane; In diethyl ether; chloroform;
DOI:10.1021/acs.orglett.5b03331

Reference yield:

: 1258278-46-4
2-benzyl-1,2,3,4-tetrahydro-1-(nitromethyl)isoquinoline

: 40615-06-3
(2-benzyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methanamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/ejoc.201000955