2-(Phenylmethyl)-3,4-dihydroisoquinolin-2-ium bromide

Base Information

Chemical Name:2-(Phenylmethyl)-3,4-dihydroisoquinolin-2-ium bromide
CAS No.:84500-82-3
Molecular Formula:Br*C₁₆H₁₆N
Molecular Weight:302.214
Hs Code.:
DSSTox Substance ID:DTXSID90511615

Synonyms:84500-82-3;2-(phenylmethyl)-3,4-dihydroisoquinolin-2-ium bromide;DTXSID90511615;2-Benzyl-3,4-dihydroisoquinolin-2-ium bromide;A840822

Suppliers and Price of 2-(Phenylmethyl)-3,4-dihydroisoquinolin-2-ium bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(Phenylmethyl)-3,4-dihydroisoquinolin-2-ium bromide

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:301.04661
Heavy Atom Count:18
Complexity:275

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C[N+](=CC2=CC=CC=C21)CC3=CC=CC=C3.[Br-]

Technology Process of 2-(Phenylmethyl)-3,4-dihydroisoquinolin-2-ium bromide

There total 5 articles about 2-(Phenylmethyl)-3,4-dihydroisoquinolin-2-ium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 3230-65-7
3,4-dihydroisoquinoline

: 100-39-0
benzyl bromide

: 84500-82-3
2-benzyl-3,4-dihydroisoquinolin-2-ium bromide

Guidance literature:: for 3.7h;
DOI:10.1002/ejoc.201000955

Reference yield:

: 91-21-4
1,2,3,4-tetrahydroisoquinoline

: 84500-82-3
2-benzyl-3,4-dihydroisoquinolin-2-ium bromide

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / acetonitrile / 0.5 h / Inert atmosphere

1.2: Reflux; Inert atmosphere

2.1: tropylium bromide / acetonitrile / 3 h / Reflux; Inert atmosphere

With tropylium bromide; potassium carbonate; In acetonitrile;
DOI:10.1021/acs.joc.7b02584