(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid

Base Information

Chemical Name:(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid
CAS No.:138812-69-8
Molecular Formula:C13H16N2O4
Molecular Weight:264.281
Hs Code.:
DSSTox Substance ID:DTXSID40363828
Mol file:138812-69-8.mol

Synonyms:138812-69-8;(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid;(S)-4-N-CBZ-PIPERAZINE-2-CARBOXYLIC ACID;(S)-4-CBZ-PIPERAZINE-2-CARBOXYLIC ACID;(2S)-4-phenylmethoxycarbonylpiperazine-2-carboxylic acid;(S)-4-((benzyloxy)carbonyl)piperazine-2-carboxylic acid;(2S)-4-[(Benzyloxy)carbonyl]piperazine-2-carboxylic acid;(R)-PIPERAZINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER;(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylicacid;SCHEMBL1485691;DTXSID40363828;MFCD02179109;AKOS015836891;AS-35442;CS-0137172;(S)-4-(Benzyloxycarbonyl)piperazine-2- carboxylic acid

Suppliers and Price of (S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylicacid 97%
1g
$ 299.00

Chemenu
(S)-4-((benzyloxy)carbonyl)piperazine-2-carboxylicacid 97%
1g
$ 282.00

Biosynth Carbosynth
(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid
250 mg
$ 350.00

Biosynth Carbosynth
(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid
50 mg
$ 125.00

Biosynth Carbosynth
(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid
1 g
$ 700.00

Biosynth Carbosynth
(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid
500 mg
$ 500.00

Biosynth Carbosynth
(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid
100 mg
$ 200.00

American Custom Chemicals Corporation
1,3-PIPERAZINEDICARBOXYLIC ACID, 1-(PHENYLMETHYL) ESTER, (3S)- 95.00%
5G
$ 1437.98

American Custom Chemicals Corporation
1,3-PIPERAZINEDICARBOXYLIC ACID, 1-(PHENYLMETHYL) ESTER, (3S)- 95.00%
250MG
$ 275.10

Alichem
(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylicacid
1g
$ 420.51

Total 24 raw suppliers

Chemical Property of (S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid

Chemical Property:

Boiling Point:465.1±45.0 °C(Predicted)
PKA:2.20±0.20(Predicted)
PSA：78.87000
Density:1.294±0.06 g/cm3(Predicted)
LogP:0.94830
Storage Temp.:2-8°C
XLogP3:-1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:264.11100700
Heavy Atom Count:19
Complexity:329

Purity/Quality:

98% ^*data from raw suppliers

(S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC(N1)C(=O)O)C(=O)OCC2=CC=CC=C2
Isomeric SMILES:C1CN(C[C@H](N1)C(=O)O)C(=O)OCC2=CC=CC=C2

Technology Process of (S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid

There total 14 articles about (S)-4-(Benzyloxycarbonyl)piperazine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: S-(-)-piperazine-2-carboxylic acid dihydrochloride

: 138812-69-8
(S)-4-(benzyloxycarbonyl)piperazine-2-carboxylic acid

Guidance literature:: S-(-)-piperazine-2-carboxylic acid dihydrochloride; With copper (II) carbonate hydroxide; potassium carbonate; In water; for 2h; Reflux;

benzyl chloroformate; In water; toluene; at 0 - 20 ℃;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 147650-70-2
(2S)-piperazine-2-carboxylic acid

: 138812-69-8
(S)-4-(benzyloxycarbonyl)piperazine-2-carboxylic acid

Guidance literature:: benzyl chloroformate; (2S)-piperazine-2-carboxylic acid; With copper(ll) sulfate pentahydrate; sodium hydrogencarbonate; sodium hydroxide; In water; at 0 - 30 ℃;

With hydrogenchloride; ethylenediaminetetraacetic acid; In water; pH=7.0;