147650-70-2 Usage
General Description
(S)-Piperazine-2-carboxylic acid, also known as L-pipecolic acid, is a cyclic amine that contains a piperazine ring and a carboxylic acid functional group. It is an important intermediate in the biosynthesis of the neurotransmitter gamma-aminobutyric acid (GABA) and is synthesized in the body from lysine. L-pipecolic acid is used as a chiral building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It also plays a role in the biosynthesis of several natural products, including biologically active alkaloids. Additionally, L-pipecolic acid has been investigated for its potential as a treatment for metabolic disorders and neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 147650-70-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,6,5 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 147650-70:
(8*1)+(7*4)+(6*7)+(5*6)+(4*5)+(3*0)+(2*7)+(1*0)=142
142 % 10 = 2
So 147650-70-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N2O2/c8-5(9)4-3-6-1-2-7-4/h4,6-7H,1-3H2,(H,8,9)/t4-/m0/s1
147650-70-2Relevant articles and documents
Deracemisation and stereoinversion of alpha-amino acids using D-amino acid oxidase and hydride reducing agents.
Beard, Timothy M,Turner, Nicholas J
, p. 246 - 247 (2002)
The deracemisation and stereoinversion of both cyclic and acyclic DL-alpha-amino acids, using porcine kidney D-amino acid oxidase (DAAO) and a hydride reducing agent (NaCNBH3-NaBH4), has been investigated.
PROCESS FOR THE PREPARATION OF A CHIRAL PIPERAZINE-2-CARBOXYLIC ACID
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Page/Page column 13; 16, (2021/11/06)
The invention relates to a novel process for the preparation of a chiral piperazine-2- carboxylic acid or of a salt thereof of the formula (I). The chiral piperazine-2-carboxylic acid derivatives of the formula (I) are key intermediates for the preparation of fused heteroaryl dihydro pyrimidines which are useful for the treatment and prophylaxis of hepatitis B virus infections.