4-acetyl-5-hydroxybenzene-1,3-diyl dibenzoate

Base Information

• Chemical Name: 4-acetyl-5-hydroxybenzene-1,3-diyl dibenzoate
• CAS No.: 115425-05-3
• Molecular Formula: C22H16O6
• Molecular Weight: 376.3588
• Mol file: 115425-05-3.mol

Synonyms:4-Acetyl-5-hydroxy-1,3-phenylene dibenzoate; Ethanone, 1-[2,4-bis(benzoyloxy)-6-hydroxyphenyl]-

Chemical Property of 4-acetyl-5-hydroxybenzene-1,3-diyl dibenzoate

Chemical Property:

• Vapor Pressure: 5.11E-15mmHg at 25°C
• Refractive Index: 1.627
• Boiling Point: 600.6°C at 760 mmHg
• Flash Point: 213.7°C
• Density: 1.314g/cm³

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-acetyl-5-hydroxybenzene-1,3-diyl dibenzoate

There total 1 articles about 4-acetyl-5-hydroxybenzene-1,3-diyl dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) + benzoyl chloride (98-88-4) → ο-Benzoyloxy-phloracetophenon (130471-75-9) + 4,6-dibenzoyloxy-2'-hydroxyacetophenone (115425-05-3)

Guidance literature:

With sodium hydroxide;

Reference yield:

4,6-dibenzoyloxy-2'-hydroxyacetophenone (115425-05-3) → 2',4',6'-trihydroxy-3-methoxychalkone (137225-57-1,56927-09-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.5 g / ethanolic KOH / 15 h / Ambient temperature

2: 0.5 g / 10percent aq. NaOH / ethanol / 5 h / Heating

With potassium hydroxide; sodium hydroxide; In ethanol;

Reference yield:

4,6-dibenzoyloxy-2'-hydroxyacetophenone (115425-05-3) + 4-methoxy-benzaldehyde (123-11-5) → 4',6'-dibenzoyloxy-2'-hydroxy-3-methoxychalkone (115425-06-4)

Guidance literature:

With potassium hydroxide; for 15h; Ambient temperature;

upstream raw materials:

2,4,6-trihydroxyacetophenone

benzoyl chloride

Downstream raw materials:

4',6'-dibenzoyloxy-2'-hydroxy-3-methoxychalkone

2',4',6'-trihydroxy-3-methoxychalkone