4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole

Base Information

Chemical Name:4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole
CAS No.:122994-69-8
Molecular Formula:C12H12ClNO2
Molecular Weight:237.68
Hs Code.:2934999090
ChEMBL ID:CHEMBL5202668
DSSTox Substance ID:DTXSID90560820
Wikidata:Q82444422
Mol file:122994-69-8.mol

Synonyms:122994-69-8;4-(chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole;4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyloxazole;4-chloromethyl-2-(4-methoxy-phenyl)-5-methyl-oxazole;Oxazole, 4-(chloromethyl)-2-(4-methoxyphenyl)-5-methyl-;SCHEMBL3538865;CHEMBL5202668;DTXSID90560820;LCZPNWWYXZSYJO-UHFFFAOYSA-N;MFCD08457265;AKOS000265987;LS-06409

Suppliers and Price of 4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole
100mg
$ 155.00

TRC
4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole
50mg
$ 90.00

TRC
4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole
10mg
$ 45.00

CHESS?
MC002036:4-Chloromethyl-2-(4-methoxy-phenyl)-5-methyl-oxazole 95
1 g
$ 504.00

American Custom Chemicals Corporation
4-(CHLOROMETHYL)-2-(4-METHOXYPHENYL)-5-METHYLOXAZOLE 95.00%
0.5G
$ 282.00

Total 7 raw suppliers

Chemical Property of 4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole

Chemical Property:

Vapor Pressure:1.61E-05mmHg at 25°C
Boiling Point:376°C at 760 mmHg
Flash Point:181.2°C
PSA：35.26000
Density:1.196g/cm³
LogP:3.39740
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:237.0556563
Heavy Atom Count:16
Complexity:219

Purity/Quality:

97% ^*data from raw suppliers

4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=C(O1)C2=CC=C(C=C2)OC)CCl

Technology Process of 4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole

There total 4 articles about 4-(Chloromethyl)-2-(4-methoxyphenyl)-5-methyl-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1336-21-6
ammonium hydroxide

: 35392-11-1
2-(4-methoxyphenyl)-4,5-dimethyloxazole N-oxide

: 122994-69-8
4-chloromethyl-2-(4-methoxy-phenyl)-5-methyl-oxazole

Guidance literature:: With trichlorophosphate; In chloroform;

Reference yield:

: 35392-11-1
2-(4-methoxyphenyl)-4,5-dimethyloxazole N-oxide

: 122994-69-8
4-chloromethyl-2-(4-methoxy-phenyl)-5-methyl-oxazole

Guidance literature:: With trichlorophosphate; In 1,2-dichloro-ethane; at 10 - 60 ℃;
DOI:10.1002/jhet.3893

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 122994-69-8
4-chloromethyl-2-(4-methoxy-phenyl)-5-methyl-oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; hydrogenchloride / 3 h / 0 °C

2: trichlorophosphate / 1,2-dichloro-ethane / 10 - 60 °C

With hydrogenchloride; acetic acid; trichlorophosphate; In 1,2-dichloro-ethane;
DOI:10.1002/jhet.3893