2-Propenoic acid, 1-methyl-2-oxo-2-phenylethyl ester

Base Information

• Chemical Name: 2-Propenoic acid, 1-methyl-2-oxo-2-phenylethyl ester
• CAS No.: 1312799-08-8
• Molecular Formula: C12H12O3
• Molecular Weight: 204.225
• Mol file: 1312799-08-8.mol

Synonyms:

Chemical Property of 2-Propenoic acid, 1-methyl-2-oxo-2-phenylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenoic acid, 1-methyl-2-oxo-2-phenylethyl ester

There total 3 articles about 2-Propenoic acid, 1-methyl-2-oxo-2-phenylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1-phenyl-propan-1-one (93-55-0) + acrylic acid (79-10-7) → 1-oxo-1-phenylpropan-2-yl acrylate (1312799-08-8)

Guidance literature:

With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In ethyl acetate; at 20 - 75 ℃; for 24h;

DOI:10.1002/anie.201101522

Reference yield: 72.0%

→ 1-oxo-1-phenylpropan-2-yl acrylate (1312799-08-8)

Guidance literature:

Reference yield: 53.0%

1-Phenyl-1-propanol (93-54-9) + acrylic acid (79-10-7) → 1-oxo-1-phenylpropan-2-yl acrylate (1312799-08-8)

Guidance literature:

With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In water; ethyl acetate; at 100 ℃; for 12h; Schlenk technique;

DOI:10.1016/j.tetlet.2017.12.030

upstream raw materials:

1-phenyl-propan-1-one

acrylic acid

1-Phenyl-1-propanol