(S)-4-chloro-diphenylmethanol

Base Information

Chemical Name:(S)-4-chloro-diphenylmethanol
CAS No.:101402-04-4
Molecular Formula:C13H11ClO
Molecular Weight:218.683
Hs Code.:
UNII:L1R622LJ8Z
Nikkaji Number:J822.809D
Wikidata:Q27282595
ChEMBL ID:CHEMBL2251569
Mol file:101402-04-4.mol

Synonyms:(S)-(4-Chlorophenyl)-phenylmethanol; (S)-α-(4-chlorophenyl)phenylmethanol; (S)-(+)-(4-chlorophenyl)phenylmethanol; (S)-(+)-1-(p-chlorophenyl)phenylmethanol

Suppliers and Price of (S)-4-chloro-diphenylmethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 50 raw suppliers

Chemical Property of (S)-4-chloro-diphenylmethanol

Chemical Property:

Melting Point:54-55 °C
Boiling Point:352.2±27.0 °C(Predicted)
PKA:13.34±0.20(Predicted)
PSA：20.23000
Density:1 +-.0.06 g/cm3(Predicted)
LogP:3.42170
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:218.0498427
Heavy Atom Count:15
Complexity:181

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=C(C=C2)Cl)O
Isomeric SMILES:C1=CC=C(C=C1)[C@@H](C2=CC=C(C=C2)Cl)O

Technology Process of (S)-4-chloro-diphenylmethanol

There total 64 articles about (S)-4-chloro-diphenylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 106-39-8
bromochlorobenzene

: 100-52-7
benzaldehyde

: 101402-04-4
(S)-4-chlorobenzhydrol

Guidance literature:: With triisopropoxytitanium(IV) chloride; phenyllithium; In diethyl ether; cyclohexane; at -78 - 20 ℃; for 0.25h; enantioselective reaction; Inert atmosphere;
DOI:10.1002/chem.201203946

Reference yield: 98.0%

: 1679-18-1
4-Chlorophenylboronic acid

: 100-52-7
benzaldehyde

: 101402-04-4
(S)-4-chlorobenzhydrol

Guidance literature:: 4-Chlorophenylboronic acid; With diethylzinc; In hexane; toluene; at 60 ℃; for 12h;

benzaldehyde; With (-)-2-exo-morpholinoisobornane-10-thiol; In hexane; toluene; at -35 ℃; for 48h;
DOI:10.1021/jo052017b

Reference yield: 98.0%

: 3262-89-3
triphenylboroxine

: 104-88-1
4-chlorobenzaldehyde

: 101402-04-4
(S)-4-chlorobenzhydrol

Guidance literature:: triphenylboroxine; With diethylzinc; In toluene; at 60 ℃; for 4h;

4-chlorobenzaldehyde; With (S)-dendritic pyrrolidinylmethanol C₁₁₆H₁₀₅NO₁₅; In toluene; at -15 ℃; for 6h;
DOI:10.1021/jo050994h