N-(5-Methoxy-2-Phenoxyphenyl)methanesulfonamide

Base Information

Chemical Name:N-(5-Methoxy-2-Phenoxyphenyl)methanesulfonamide
CAS No.:123664-84-6
Molecular Formula:C14H15NO4S
Molecular Weight:293.343
Hs Code.:2935009090
DSSTox Substance ID:DTXSID10445180
Nikkaji Number:J1.226.989G
Wikidata:Q82263530
Mol file:123664-84-6.mol

Synonyms:N-(5-Methoxy-2-Phenoxyphenyl)methanesulfonamide;123664-84-6;Methanesulfonamide, N-(5-methoxy-2-phenoxyphenyl)-;SCHEMBL10416920;DTXSID10445180;HKQJXMJGWKDFTA-UHFFFAOYSA-N;3-methylsulfonylamino4-phenoxyanisole;MFCD13152085;3-methylsulfonylamino-4-phenoxyanisole;AKOS015896222;CS-W022900;DS-18534;FT-0657420;C71932;N-(2-Phenoxy-5-methoxyphenyl)methanesulfonamide;N-(5-Methoxy-2-phenoxyphenyl)-methanesulfonamide;A890661

Suppliers and Price of N-(5-Methoxy-2-Phenoxyphenyl)methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(5-Methoxy-2-phenoxyphenyl)methanesulfonamide 98%
5g
$ 728.00

Crysdot
N-(5-Methoxy-2-phenoxyphenyl)methanesulfonamide 98%
1g
$ 260.00

Chemenu
N-(5-methoxy-2-phenoxyphenyl)methanesulfonamide 95+%
1g
$ 247.00

Chemenu
N-(5-methoxy-2-phenoxyphenyl)methanesulfonamide 95+%
5g
$ 688.00

American Custom Chemicals Corporation
N-(5-METHOXY-2-PHENOXYPHENYL)METHANESULFONAMIDE 95.00%
10G
$ 1334.03

American Custom Chemicals Corporation
N-(5-METHOXY-2-PHENOXYPHENYL)METHANESULFONAMIDE 95.00%
5G
$ 909.56

Ambeed
N-(5-Methoxy-2-phenoxyphenyl)methanesulfonamide 98%
250mg
$ 19.00

Ambeed
N-(5-Methoxy-2-phenoxyphenyl)methanesulfonamide 98%
100mg
$ 19.00

Ambeed
N-(5-Methoxy-2-phenoxyphenyl)methanesulfonamide 98%
5g
$ 74.00

Ambeed
N-(5-Methoxy-2-phenoxyphenyl)methanesulfonamide 98%
1g
$ 74.00

Total 33 raw suppliers

Chemical Property of N-(5-Methoxy-2-Phenoxyphenyl)methanesulfonamide

Chemical Property:

Boiling Point:411.4±55.0 °C(Predicted)
PKA:8.07±0.10(Predicted)
PSA：73.01000
Density:1.306±0.06 g/cm3(Predicted)
LogP:4.01280
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:293.07217913
Heavy Atom Count:20
Complexity:387

Purity/Quality:

99%, ^*data from raw suppliers

N-(5-Methoxy-2-phenoxyphenyl)methanesulfonamide 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)OC2=CC=CC=C2)NS(=O)(=O)C

Technology Process of N-(5-Methoxy-2-Phenoxyphenyl)methanesulfonamide

There total 5 articles about N-(5-Methoxy-2-Phenoxyphenyl)methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.9%

: 76838-72-7
5-methoxy-2-phenoxyaniline

: 124-63-0
methanesulfonyl chloride

: 123664-84-6
N-(5-methoxy-2-phenoxyphenyl)methanesulfonamide

Guidance literature:: With hydrogenchloride; In pyridine; water; ethyl acetate;

Reference yield:

: 84594-95-6
5-methoxy-1-nitro-2-phenoxybenzene

: 123664-84-6
N-(5-methoxy-2-phenoxyphenyl)methanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / 4N aq. HCl; Fe / ethanol / 0.33 h / 65 - 70 °C

2: 82 percent / pyridine / 1 h / 20 °C

With pyridine; hydrogenchloride; iron; In ethanol; 1: Reduction / 2: Mesylation;
DOI:10.1248/cpb.48.131

Reference yield:

: 10298-80-3
2-chloro-5-methoxynitrobenzene

: 123664-84-6
N-(5-methoxy-2-phenoxyphenyl)methanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / potassium tert-butoxide / dimethylformamide / 4 h / 110 °C

2: 72 percent / 4N aq. HCl; Fe / ethanol / 0.33 h / 65 - 70 °C

3: 82 percent / pyridine / 1 h / 20 °C

With pyridine; hydrogenchloride; potassium tert-butylate; iron; In ethanol; N,N-dimethyl-formamide; 1: Substitution / 2: Reduction / 3: Mesylation;
DOI:10.1248/cpb.48.131