1-Tert-butyl 3-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate

Base Information

Chemical Name:1-Tert-butyl 3-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate
CAS No.:324769-00-8
Molecular Formula:C14H23NO5
Molecular Weight:285.34
Hs Code.:2933399090
DSSTox Substance ID:DTXSID00591549
Mol file:324769-00-8.mol

Synonyms:324769-00-8;1-tert-butyl 3-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate;1-O-tert-butyl 3-O-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate;Methyl 1-Boc-3-ethyl-4-oxopiperidine-3-carboxylate;MFCD11617898;1-(tert-butyl) 3-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate;SCHEMBL6333649;DTXSID00591549;OEMQALJIGCZHRG-UHFFFAOYSA-N;1-tert-Butyl3-methyl3-ethyl-4-oxopiperidine-1,3-dicarboxylate;ZMA76900;AKOS016014180;AS-71585;SY287401;DB-068638;CS-0061443;W17460;A850524;J-505135;benzyl-4-(chlorocarbonyl)tetrahydro-1(2H)-pyridinecarboxylate;1-(t-Butyl) 3-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate;Methyl 1-tert-butoxycarbonyl-4-oxo-3-ethyl-3-piperidinecarboxylate;3-ethyl-4-oxo-piperidine-1,3-dicarboxylic acid 1-tert-butyl 3-methyl ester

Suppliers and Price of 1-Tert-butyl 3-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-tert-Butyl3-methyl3-ethyl-4-oxopiperidine-1,3-dicarboxylate 95+%
1g
$ 614.00

Chemenu
1-(tert-butyl)3-methyl3-ethyl-4-oxopiperidine-1,3-dicarboxylate 95%
1g
$ 580.00

American Custom Chemicals Corporation
1-TERT-BUTYL-3-METHYL 3-ETHYL-4-OXOPIPERIDINE-1,3-DICARBOXYLATE 95.00%
5MG
$ 503.55

Alichem
1-tert-Butyl3-methyl3-ethyl-4-oxopiperidine-1,3-dicarboxylate
1g
$ 540.00

AK Scientific
1-tert-butyl3-methyl3-ethyl-4-oxopiperidine-1,3-dicarboxylate
1g
$ 1035.20

Total 13 raw suppliers

Chemical Property of 1-Tert-butyl 3-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate

Chemical Property:

PSA：72.91000
LogP:1.70360
Storage Temp.:2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:285.15762283
Heavy Atom Count:20
Complexity:412

Purity/Quality:

97% ^*data from raw suppliers

1-tert-Butyl3-methyl3-ethyl-4-oxopiperidine-1,3-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1(CN(CCC1=O)C(=O)OC(C)(C)C)C(=O)OC

Technology Process of 1-Tert-butyl 3-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate

There total 3 articles about 1-Tert-butyl 3-methyl 3-ethyl-4-oxopiperidine-1,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 75-03-6
ethyl iodide

: 161491-24-3
methyl 1-tert-butoxycarbonyl-4-oxo-3-piperidinecarboxylate

: 324769-00-8
methyl 1-tert-butoxycarbonyl-4-oxo-3-ethyl-3-piperidinecarboxylate

Guidance literature:: With potassium tert-butylate; In tert-butyl alcohol; at 70 ℃; for 16.5h; Heating / reflux;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 71486-53-8
methyl 4-oxo-3-piperidinecarboxylate hydrochloride

: 324769-00-8
methyl 1-tert-butoxycarbonyl-4-oxo-3-ethyl-3-piperidinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / dichloromethane; water / 20 °C

1.2: 21 h / 20 °C

2.1: potassium tert-butylate / tert-butyl alcohol / 16.5 h / 70 °C / Heating / reflux

With potassium tert-butylate; sodium hydrogencarbonate; In dichloromethane; water; tert-butyl alcohol;