AMINO-(4-METHOXY-PHENYL)-ACETIC ACID HCL

Base Information

• Chemical Name: AMINO-(4-METHOXY-PHENYL)-ACETIC ACID HCL
• CAS No.: 134722-07-9
• Molecular Formula: C₉H₁₁NO₃*ClH
• Molecular Weight: 217.652
• Hs Code.: 2922509090
• Mol file: 134722-07-9.mol

Synonyms:2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACID HYDROCHLORIDE;AMINO-(4-METHOXY-PHENYL)-ACETIC ACID HCL;AMINO(4-METHOXYPHENYL)ACETIC ACID HYDROCHLORIDE;alpha-Amino-4-methoxybenzeneacetic acid hydrochloride

Chemical Property of AMINO-(4-METHOXY-PHENYL)-ACETIC ACID HCL

Chemical Property:

• PSA: 72.55000
• LogP: 2.28190
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-2-(4-methoxyphenyl)aceticacidhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of AMINO-(4-METHOXY-PHENYL)-ACETIC ACID HCL

There total 3 articles about AMINO-(4-METHOXY-PHENYL)-ACETIC ACID HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

(S,S)-α-(4-methoxyphenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride (1313219-17-8) → (S)-α-amino-α(4-methoxyphenyl)acetic acid hydrochloride (78263-53-3,78263-54-4,134722-07-9)

Guidance literature:

With hydrogenchloride; water; at 90 ℃;

DOI:10.1021/jo200528s

Reference yield:

2-(4-methoxyphenyl)glycine (2540-53-6,19789-59-4) → amino(3-chloro-4-methoxyphenyl)acetic acid hydrochloride (134722-07-9)

Guidance literature:

With sulfuryl dichloride; acetic acid; In diethyl ether; at 20 ℃;

DOI:10.1055/s-2003-37362

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → (S)-α-amino-α(4-methoxyphenyl)acetic acid hydrochloride (78263-53-3,78263-54-4,134722-07-9)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; water / 16 h / 20 °C

2: hydrogenchloride; water / 90 °C

With hydrogenchloride; water; In methanol; water; 1: Strecker amino acid synthesis;

DOI:10.1021/jo200528s

upstream raw materials:

2-(4-methoxyphenyl)glycine

(S,S)-α-(4-methoxyphenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride

4-methoxy-benzaldehyde

Downstream raw materials:

amino(3-chloro-4-methoxyphenyl)acetic acid methyl ester hydrochloride

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