N-Phenyl-1-(2-phenylethyl)-4-piperidinamine hydrochloride

Base Information

• Chemical Name: N-Phenyl-1-(2-phenylethyl)-4-piperidinamine hydrochloride
• CAS No.: 24775-76-6
• Molecular Formula: C19H24N2.2(HCl)
• Molecular Weight: 353.33
• Mol file: 24775-76-6.mol

Synonyms:N-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINAMINE HYDROCHLORIDE

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Chemical Property of N-Phenyl-1-(2-phenylethyl)-4-piperidinamine hydrochloride

Chemical Property:

• PSA: 15.27000
• LogP: 5.42050

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Phenyl-1-(2-phenylethyl)-4-piperidinamine hydrochloride

There total 1 articles about N-Phenyl-1-(2-phenylethyl)-4-piperidinamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-(2-phenylethyl)-4-piperidinone (39742-60-4) + aniline (62-53-3) → 4-anilino-N-(phenethyl)-4-piperidine bis hydrochloride (24775-76-6)

Guidance literature:

1-(2-phenylethyl)-4-piperidinone; aniline; In methanol; for 0.0833333h;

With 5-ethyl-2-methylpyridine borane complex; acetic acid; In methanol; for 22h;

With hydrogenchloride; In methanol; isopropyl alcohol; for 2h; Solvent; Reagent/catalyst;

Reference yield:

4-anilino-N-(phenethyl)-4-piperidine bis hydrochloride (24775-76-6) + propionyl chloride (79-03-8) → N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide (437-38-7)

Guidance literature:

With triethylamine; In ethyl acetate; at 55 ℃; for 2.05h; Reagent/catalyst; Solvent;

upstream raw materials:

1-(2-phenylethyl)-4-piperidinone

aniline

Downstream raw materials:

N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide

Refernces