3,5-Dibromo-2-(trifluoromethyl)pyridine

Base Information

Chemical Name:3,5-Dibromo-2-(trifluoromethyl)pyridine
CAS No.:436799-35-8
Molecular Formula:C6H2Br2F3N
Molecular Weight:304.89
Hs Code.:2933399990
DSSTox Substance ID:DTXSID50453183
Nikkaji Number:J1.688.877J
Wikidata:Q82274248
Mol file:436799-35-8.mol

Synonyms:3,5-dibromo-2-(trifluoromethyl)pyridine;436799-35-8;SCHEMBL2256015;DTXSID50453183;MFCD08741349;AKOS016006639;AT22214;SB21197;2-(Trifluoromethyl)-3,5-dibromopyridine;CS-0268500;EN300-117688

Suppliers and Price of 3,5-Dibromo-2-(trifluoromethyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
3,5-dibromo-2-(trifluoromethyl)pyridine 95%
1g
$ 580.00

American Custom Chemicals Corporation
3,5-DIBROMO-2-(TRIFLUOROMETHYL)PYRIDINE 95.00%
5MG
$ 501.30

Alichem
3,5-Dibromo-2-(trifluoromethyl)pyridine
1g
$ 490.00

Total 5 raw suppliers

Chemical Property of 3,5-Dibromo-2-(trifluoromethyl)pyridine

Chemical Property:

Boiling Point:219.1±35.0 °C(Predicted)
PKA:-4.18±0.32(Predicted)
PSA：12.89000
Density:2.052±0.06 g/cm3(Predicted)
LogP:3.62540
Storage Temp.:2-8°C
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:304.84856
Heavy Atom Count:12
Complexity:161

Purity/Quality:

97% ^*data from raw suppliers

3,5-dibromo-2-(trifluoromethyl)pyridine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC(=C1Br)C(F)(F)F)Br

Technology Process of 3,5-Dibromo-2-(trifluoromethyl)pyridine

There total 3 articles about 3,5-Dibromo-2-(trifluoromethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 436799-34-7
3,5-dibromo-2-iodopyridine

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 436799-35-8
3,5-dibromo-2-(trifluoromethyl)pyridine

Guidance literature:: With potassium fluoride; copper(l) iodide; In 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide; at 25 ℃; for 6h;
DOI:10.1002/1099-0690(20021)2002:2<327::AID-EJOC327>3.0.CO;2-V

Reference yield: 45.0%

: 625-92-3
3,5-dibromopyridine

: 14353-88-9
iodopentafluorobenzene bis(trifluoroacetate)

: 436799-35-8
3,5-dibromo-2-(trifluoromethyl)pyridine

Guidance literature:: With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; In acetonitrile; at 35 ℃; for 12h; Irradiation; Inert atmosphere;
DOI:10.1021/acscatal.7b03990

Reference yield:

: 75806-85-8
2,3,5-tribromopyridine

: 436799-35-8
3,5-dibromo-2-(trifluoromethyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: nBuLi / hexane; toluene / 0.75 h / -75 °C

1.2: 75 percent / I₂ / hexane; toluene / 2 h / -75 °C

2.1: 59 percent / KF; CuI / dimethylformamide; 1-methyl-pyrrolidin-2-one / 6 h / 25 °C

With potassium fluoride; copper(l) iodide; n-butyllithium; In 1-methyl-pyrrolidin-2-one; hexane; N,N-dimethyl-formamide; toluene;
DOI:10.1002/1099-0690(20021)2002:2<327::AID-EJOC327>3.0.CO;2-V