(5-acetyl-2-ethoxycarbonyl-1H-indol-3-yl)methyl-dimethylazanium chloride

Base Information

Chemical Name:(5-acetyl-2-ethoxycarbonyl-1H-indol-3-yl)methyl-dimethylazanium chloride
CAS No.:72873-27-9
Molecular Formula:C9H17NO2
Molecular Weight:171.239
Hs Code.:

Synonyms:L-Ala cyclohexyl ester;L-alanine cyclohexyl ester;(S)-2-Amino-propionic acid cyclohexyl ester;

Suppliers and Price of (5-acetyl-2-ethoxycarbonyl-1H-indol-3-yl)methyl-dimethylazanium chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (5-acetyl-2-ethoxycarbonyl-1H-indol-3-yl)methyl-dimethylazanium chloride

Chemical Property:

PSA：52.32000
LogP:1.90980

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (5-acetyl-2-ethoxycarbonyl-1H-indol-3-yl)methyl-dimethylazanium chloride

There total 5 articles about (5-acetyl-2-ethoxycarbonyl-1H-indol-3-yl)methyl-dimethylazanium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: (S)-cyclohexyl 2-(tert-butoxycarbonylamino)propanoate

: 72873-27-9
(S)-cyclohexyl 2-aminopropanoate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 18h;

Reference yield:

: Z-L-Ala cyclohexyl ester

: 72873-27-9
(S)-cyclohexyl 2-aminopropanoate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 20 ℃; for 2h;
DOI:10.1039/c1ob06074k

Reference yield:

: 108-93-0
cyclohexanol

: 72873-27-9
(S)-cyclohexyl 2-aminopropanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

1.2: 0.08 h / 0 °C / Inert atmosphere

1.3: 0 - 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 0.5 h / 0 - 20 °C / Inert atmosphere

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In dichloromethane;
DOI:10.1139/cjc-2017-0732