1-[(4-Methoxyphenyl)methyl]-3-(phenylseleno)-2-piperidinone

Base Information

Chemical Name:1-[(4-Methoxyphenyl)methyl]-3-(phenylseleno)-2-piperidinone
CAS No.:128773-77-3
Molecular Formula:C₁₉H₂₁NO₂Se
Molecular Weight:374.341
Hs Code.:
DSSTox Substance ID:DTXSID101188537

Synonyms:1-[(4-Methoxyphenyl)methyl]-3-(phenylseleno)-2-piperidinone;DTXSID101188537;128773-77-3

Suppliers and Price of 1-[(4-Methoxyphenyl)methyl]-3-(phenylseleno)-2-piperidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-[(4-Methoxyphenyl)methyl]-3-(phenylseleno)-2-piperidinone

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:375.07375
Heavy Atom Count:23
Complexity:376

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CN2CCCC(C2=O)[Se]C3=CC=CC=C3

Technology Process of 1-[(4-Methoxyphenyl)methyl]-3-(phenylseleno)-2-piperidinone

There total 3 articles about 1-[(4-Methoxyphenyl)methyl]-3-(phenylseleno)-2-piperidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 105-13-5
4-Methoxybenzyl alcohol

: 128773-77-3
1-(4-Methoxy-benzyl)-3-phenylselanyl-piperidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

2: 1) lithium diisopropylamide, 2) hexamethylphosphoramide / 1) THF, hexane, -78 deg C, 35 min, 2) THF, -78 deg C, 30 min

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide;
DOI:10.1021/jo00048a021

Reference yield:

: 675-20-7
piperidin-2-one

: 128773-77-3
1-(4-Methoxy-benzyl)-3-phenylselanyl-piperidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

2: 1) lithium diisopropylamide, 2) hexamethylphosphoramide / 1) THF, hexane, -78 deg C, 35 min, 2) THF, -78 deg C, 30 min

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide;
DOI:10.1021/jo00048a021

Reference yield:

: 14670-03-2
p-methoxybenzyl tosylate

: 128773-77-3
1-(4-Methoxy-benzyl)-3-phenylselanyl-piperidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / NaH

2: 94 percent / 1.) lithium diisopropylamide

With sodium hydride; lithium diisopropyl amide;
DOI:10.1016/S0040-4039(00)88731-6