(5-chloro-2-methylphenyl)methanol

Base Information

• Chemical Name: (5-chloro-2-methylphenyl)methanol
• CAS No.: 58966-29-3
• Molecular Formula: C8H9ClO
• Molecular Weight: 156.612
• Hs Code.: 2906299090
• Mol file: 58966-29-3.mol

Synonyms:(5-CHLORO-2-METHYL-PHENYL)-METHANOL;(5-Chloro-2-methylphenyl)methanol;2-Methyl-5-chlorbenzylalkohol;

Chemical Property of (5-chloro-2-methylphenyl)methanol

Chemical Property:

• PSA: 20.23000
• LogP: 2.14070

Purity/Quality:

97% ^*data from raw suppliers

(5-Chloro-2-methylphenyl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5-chloro-2-methylphenyl)methanol

There total 4 articles about (5-chloro-2-methylphenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-chloro-2-methylbenzoic acid (7499-06-1) → (5-chloro-2-methylphenyl)methanol (58966-29-3)

Guidance literature:

With dimethylsulfide borane complex; In 2-methyltetrahydrofuran; at 0 - 10 ℃; for 1h;

Reference yield:

5-chloro-2-methylbenzaldehyde (58966-34-0) → (5-chloro-2-methylphenyl)methanol (58966-29-3)

Guidance literature:

With sodium tetrahydroborate; In methanol;

Reference yield:

4-chloro-1,2-dimethylbenzene (615-60-1) → (5-chloro-2-methylphenyl)methanol (58966-29-3) + 2-methyl-4-chlorobenzyl alcohol (129716-11-6)

Guidance literature:

With NADPH generating system; rat liver microsomes; In water; at 35 - 36 ℃; for 1h; Product distribution; Mechanism; or 4-tert-butyl-1,2-dimethylbenzene;

DOI:10.1016/S0040-4039(00)97427-6

upstream raw materials:

5-chloro-2-methylbenzaldehyde

formaldehyd

4-chloro-1,2-dimethylbenzene

5-chloro-2-methylbenzoic acid

Downstream raw materials:

5-chloro-2-methyl-benzyl bromide

2-methyl-5-chlorobenzyl chloride

Ethyl-2-methyl-5-chlorbenzylsulfon

Ethyl-2-methyl-5-chlorbenzylsulfid