5,6-Dimethoxynicotinaldehyde

Base Information

Chemical Name:5,6-Dimethoxynicotinaldehyde
CAS No.:52605-99-9
Molecular Formula:C8H9NO3
Molecular Weight:167.164
Hs Code.:2933399090
DSSTox Substance ID:DTXSID20557127
Wikidata:Q82438914
Mol file:52605-99-9.mol

Synonyms:5,6-Dimethoxynicotinaldehyde;52605-99-9;5,6-dimethoxypyridine-3-carbaldehyde;3-Pyridinecarboxaldehyde, 5,6-dimethoxy-;SCHEMBL2698927;DTXSID20557127;BVQOHVMOURVZMO-UHFFFAOYSA-N;AMY18395;CCA60599;MFCD11857649;2,3-Dimethoxypyridine-5-Carbaldehyde;AKOS006344564;CS-W017844;SB52686;5,6-Dimethoxynicotinaldehyde, AldrichCPR;AS-59271;EN300-268715;A857407;Z1201625962

Suppliers and Price of 5,6-Dimethoxynicotinaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
5,6-Dimethoxynicotinaldehyde Aldrich
1g
$ 637.00

Matrix Scientific
5,6-Dimethoxynicotinaldehyde
250mg
$ 394.00

Crysdot
5,6-Dimethoxynicotinaldehyde 95+%
5g
$ 1140.00

Crysdot
5,6-Dimethoxynicotinaldehyde 95+%
1g
$ 380.00

ChemScene
5,6-Dimethoxynicotinaldehyde
250mg
$ 268.00

ChemScene
5,6-Dimethoxynicotinaldehyde
100mg
$ 161.00

ChemScene
5,6-Dimethoxynicotinaldehyde
1g
$ 535.00

Chemenu
5,6-dimethoxynicotinaldehyde 95%
5g
$ 1066.00

Chemenu
5,6-dimethoxynicotinaldehyde 95%
1g
$ 355.00

Apolloscientific
5,6-Dimethoxynicotinaldehyde 98%
1g
$ 495.00

Total 27 raw suppliers

Chemical Property of 5,6-Dimethoxynicotinaldehyde

Chemical Property:

Boiling Point:277.8±35.0 °C(Predicted)
PKA:2.45±0.10(Predicted)
PSA：48.42000
Density:1.174±0.06 g/cm3(Predicted)
LogP:0.91130
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:167.058243149
Heavy Atom Count:12
Complexity:151

Purity/Quality:

98% ^*data from raw suppliers

5,6-Dimethoxynicotinaldehyde Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 43
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(N=CC(=C1)C=O)OC

Technology Process of 5,6-Dimethoxynicotinaldehyde

There total 7 articles about 5,6-Dimethoxynicotinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 52605-98-8
5-bromo-2,3-dimethoxypyridine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 52605-99-9
5-formyl-2,3-dimethoxypyridine

Guidance literature:: 5-bromo-2,3-dimethoxypyridine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

Reference yield:

: 1428797-03-8
2,3-dimethoxy-5-vinylpyridine

: 52605-99-9
5-formyl-2,3-dimethoxypyridine

Guidance literature:: 2,3-dimethoxy-5-vinylpyridine; With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In tetrahydrofuran; water; at 25 ℃; for 0.5h;

With sodium periodate; In tetrahydrofuran; water; at 25 ℃; for 12h;

Reference yield:

: 52605-96-6
2-chloro-3-methoxypyridine

: 52605-99-9
5-formyl-2,3-dimethoxypyridine

Guidance literature:: Multi-step reaction with 3 steps

1: methanol

2: Br₂ / acetic acid

3: n-BuLi

With n-butyllithium; bromine; In methanol; acetic acid;
DOI:10.1016/j.bmc.2003.08.029