1-[(4-Methoxyphenyl)Methyl]-1H-1,2,3-triazole-4- carboxylic acid

Base Information

Chemical Name:1-[(4-Methoxyphenyl)Methyl]-1H-1,2,3-triazole-4- carboxylic acid
CAS No.:716361-79-4
Molecular Formula:C11H11N3O3
Molecular Weight:233.227
Hs Code.:
Mol file:716361-79-4.mol

Synonyms:WECC-0007320;1-p-methoxybenzyl-1H-1,2,3-triazole-4-carboxylic acid;

Suppliers and Price of 1-[(4-Methoxyphenyl)Methyl]-1H-1,2,3-triazole-4- carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 6 raw suppliers

Chemical Property of 1-[(4-Methoxyphenyl)Methyl]-1H-1,2,3-triazole-4- carboxylic acid

Chemical Property:

Melting Point:184.1 - 184.7 °C
PSA：77.24000
LogP:1.03320

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 1-[(4-Methoxyphenyl)Methyl]-1H-1,2,3-triazole-4- carboxylic acid

There total 9 articles about 1-[(4-Methoxyphenyl)Methyl]-1H-1,2,3-triazole-4- carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 81581-05-7
ethyl 1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxylate

: 716361-79-4
1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxylic acid

Guidance literature:: ethyl 1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxylate; With methanol; lithium hydroxide; water; at 0 - 20 ℃;

With hydrogenchloride; water; pH=3 - 4;

Reference yield: 87.0%

: 70978-37-9
1-(azidomethyl)-4-methoxybenzene

: 471-25-0
Propiolic acid

: 716361-79-4
1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxylic acid

Guidance literature:: With copper(II) acetate monohydrate; sodium L-ascorbate; In water; tert-butyl alcohol; at 20 ℃; for 14h;
DOI:10.1039/C8MD00491A

Reference yield: 72.0%

: 1-(4-methoxybenzyl)-4-bromo-1H-1,2,3-triazole

: 74-88-4
methyl iodide

: 716361-79-4
1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxylic acid

Guidance literature:: 1-(4-methoxybenzyl)-4-bromo-1H-1,2,3-triazole; With TurboGrignard; In tetrahydrofuran; at 0 - 30 ℃; for 1h;

methyl iodide; With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 - 30 ℃; for 48h;